[PDF][PDF] Conventional and monocyte-derived CD11b+ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen

M Plantinga, M Guilliams, M Vanheerswynghels… - Immunity, 2013 - cell.com
Dendritic cells (DCs) are crucial for mounting allergic airway inflammation, but it is unclear
which subset of DCs performs this task. By using CD64 and MAR-1 staining, we reliably …

[HTML][HTML] DAMPs activating innate and adaptive immune responses in COPD

SD Pouwels, IH Heijink, NH Ten Hacken… - Mucosal …, 2014 - Elsevier
Chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized
by sustained neutrophilic airway inflammation, is caused by chronic exposure to noxious …

Functional plasticity of human respiratory tract dendritic cells: GM-CSF enhances TH2 development

A Faith, J McDonald, E Peek, D Richards… - Journal of allergy and …, 2005 - Elsevier
BACKGROUND: Dendritic cells within the human respiratory mucosa (RTDCs) are proposed
to initiate immune responses to foreign antigens. Their capacity to polarize T-cell responses …

D er p2 recombinant bacille C almette‐G uerin priming of bone marrow‐derived dendritic cells suppresses D er p2‐induced T helper17 function in a mouse model of …

SY Qu, HF Ou‐yang, YL He, ZK Li, JR Shi… - …, 2014 - Wiley Online Library
Background and objective Previous studies have demonstrated that our recombinant bacille
C almette‐G uerin (rBCG), which expresses D er p2 in house dust mite (D er p2 rBCG) …

Taking our breath away: dendritic cells in the pathogenesis of asthma

BN Lambrecht, H Hammad - Nature Reviews Immunology, 2003 - nature.com
Dendritic cells (DCs) are mainly known for their capacity to induce primary immune
responses. Here, we propose that DCs are similarly essential for controlling effector T-cell …

Adipose‐derived stem cells ameliorate allergic airway inflammation by inducing regulatory T cells in a mouse model of asthma

KS Cho, MK Park, SA Kang, HY Park… - Mediators of …, 2014 - Wiley Online Library
Although several studies have demonstrated that mesenchymal stem cells derived from
adipose tissue (ASCs) can ameliorate allergic airway inflammation, the immunomodulatory …

[HTML][HTML] C5a receptor signalling in dendritic cells controls the development of maladaptive Th2 and Th17 immunity in experimental allergic asthma

I Schmudde, HA Ströver, T Vollbrandt, P König… - Mucosal …, 2013 - nature.com
The pathways underlying dendritic cell (DC) activation in allergic asthma are incompletely
understood. Here we demonstrate that adoptive transfer of ovalbumin-pulsed wild-type (wt) …

Interactions between airway epithelial cells and dendritic cells: implications for the regulation of airway inflammation

JW Upham, SM Stick - Current drug targets, 2006 - ingentaconnect.com
Airway epithelial cells (AEC) and dendritic cells (DC) are situated in close proximity within
the airway epithelium, and are the first cells to encounter inhaled pathogens, allergens and …

Innate lymphoid cells contribute to allergic airway disease exacerbation by obesity

L Everaere, S Ait-Yahia, O Molendi-Coste… - Journal of Allergy and …, 2016 - Elsevier
Background Epidemiologic and clinical observations identify obesity as an important risk
factor for asthma exacerbation, but the underlying mechanisms remain poorly understood …

Dendritic cell and epithelial cell interactions at the origin of murine asthma

BN Lambrecht, H Hammad - Annals of the American Thoracic …, 2014 - atsjournals.org
Dendritic cells (DCs) are ideally placed in the airways and lungs to capture inhaled
allergens. Different subsets of DCs perform different tasks. Migratory conventional DCs …