Environmental pollutants and the risk of neurological disorders

L Aleya, MS Uddin - Environmental Science and Pollution Research, 2020 - Springer
Neurological disorders have attracted considerable attention in the last decades owing to
their large burden on global health. Currently, about 100 million people worldwide are …

Acute Ochratoxin A exposure induces inflammation and apoptosis in human embryonic kidney (HEK293) cells

S Raghubeer, S Nagiah, AA Chuturgoon - Toxicon, 2017 - Elsevier
Ochratoxin A (OTA), a common contaminant of grain and fruit and known carcinogen, has
been linked to impaired antioxidant response and cellular repair. The effect of OTA on …

Induction of genotoxic effects and modulation of the intracellular calcium level in syrian hamster embryo (SHE) fibroblasts caused by ochratoxin A

E Dopp, J Müller, C Hahnel, D Schiffmann - Food and chemical toxicology, 1999 - Elsevier
The mycotoxin ochratoxin A (OTA) is a naturally occuring contaminant of food. The genotoxic
status of OTA is still controversial because contradictory results were obtained in various …

Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes

CA Gonzalez-Arias, AB Benitez-Trinidad… - Food and chemical …, 2014 - Elsevier
The contamination of food commodities by fungal toxins has attracted great interest because
many of these mycotoxins are responsible for different diseases, including cancer and other …

Ochratoxin A causes DNA damage and cytogenetic effects but no DNA adducts in rats

A Mally, G Pepe, S Ravoori, M Fiore… - Chemical research in …, 2005 - ACS Publications
Ochratoxin A (OTA) is a potent nephrotoxin and renal carcinogen in rats, but the mechanism
of OTA tumorigenicity is unknown. Ochratoxin A has been shown to be negative in many …

Acute neurotoxic effects of the fungal metabolite ochratoxin-A

V Sava, O Reunova, A Velasquez, R Harbison… - Neurotoxicology, 2006 - Elsevier
Ochratoxin-A (OTA) is a fungal metabolite with potential toxic effects on the central nervous
system that have not yet been fully characterized. OTA has complex mechanisms of action …

Ochratoxin A-induced DNA damage in human fibroblast: protective effect of cyanidin 3-O-β-D-glucoside

A Russo, L La Fauci, R Acquaviva, A Campisi… - The Journal of …, 2005 - Elsevier
Ochratoxin A (OTA), a mycotoxin produced by Aspergillus ochraceus and other moulds, has
recently received growing attention because of its carcinogenic, teratogenic and nephrotoxic …

Ochratoxin A: molecular interactions, mechanisms of toxicity and prevention at the molecular level

T Kőszegi, M Poór - Toxins, 2016 - mdpi.com
Ochratoxin A (OTA) is a widely-spread mycotoxin all over the world causing major health
risks. The focus of the present review is on the molecular and cellular interactions of OTA. In …

Detection of ochratoxin A-induced DNA damage in MDCK cells by alkaline single cell gel electrophoresis (comet assay)

S Lebrun, W Föllmann - Archives of toxicology, 2002 - Springer
The mycotoxin ochratoxin A (OTA), a widespread contaminant of food and feedstuffs, is
nephrotoxic, immunosuppressive and carcinogenic in domestic and laboratory animals …

Ochratoxin A-induced mutagenesis in mammalian cells is consistent with the production of oxidative stress

N Palma, S Cinelli, O Sapora, SH Wilson… - Chemical research in …, 2007 - ACS Publications
Ochratoxin A (OTA) is a widespread mycotoxin in food and a powerful nephrocarcinogen in
rats. The mutagenicity of OTA has been extensively investigated but with conflicting results …