Recent advances in the neurobiology and neurogenerative diseases have attracted growing
interest in exosomes and their ability to carry and propagate active biomolecules as a …

The pathogenesis of amyotrophic lateral sclerosis (ALS), a lethal neurodegenerative
disease, remains undisclosed. Mutations in ALS related genes have been identified, albeit …

Extracellular vesicles (EVs) are small reservoirs of different molecules and important
mediators of cell-to-cell communication. As putative vehicles of misfolded protein …

Exosomes are small extracellular vesicles with a complex lipid-bilayer surface and 30–150
nm diameter. These vesicles play a critical role in intercellular signaling networks during …

Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and
molecular observations suggest that ALS pathology originates at a single site and spreads …

Microglia play an important role in neurodegenerative disease [ie, Parkinson's disease (PD),
Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS)]. These diseases share …

Originating from slow irreversible and progressive loss and dysfunction of neurons and
synapses in the nervous system, neurodegenerative diseases (NDDs) affect millions of …

Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder
affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous …

Exosomes are bilipid layer‐enclosed vesicles derived from endosomes and are released
from neural cells. They contain a diversity of proteins, mRNAs, and microRNAs (miRNAs) …