Muscle and neuronal nicotinic acetylcholine receptors: structure, function and pathogenicity
D Kalamida, K Poulas, V Avramopoulou… - The FEBS …, 2007 - Wiley Online Library
Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …
Nicotinic receptors in human brain: topography and pathology
JA Court, C Martin-Ruiz, A Graham, E Perry - Journal of chemical …, 2000 - Elsevier
Brain nicotinic acetylcholine receptors (nAChR) are a class of ligand-gated channels
composed of α and β subunits with specific structural, functional and pharmacological …
composed of α and β subunits with specific structural, functional and pharmacological …
Identification of sequence motifs that target neuronal nicotinic receptors to dendrites and axons
J Xu, Y Zhu, SF Heinemann - Journal of Neuroscience, 2006 - Soc Neuroscience
Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a family of ligand-gated ion
channels that play important roles in central and peripheral nervous systems. The …
channels that play important roles in central and peripheral nervous systems. The …
Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells
LC Gahring, SW Rogers - The AAPS journal, 2005 - Springer
Of the thousands of proven carcinogens and toxic agents contained within a cigarette,
nicotine, while being the addictive agent, is often viewed as the least harmful of these …
nicotine, while being the addictive agent, is often viewed as the least harmful of these …
Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus
AJ Graham, MA Ray, EK Perry, E Jaros… - Journal of chemical …, 2003 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels
composed of α and β subunits with specific structural, functional and pharmacological …
composed of α and β subunits with specific structural, functional and pharmacological …
Heterogeneity and regulation of nicotinic acetylcholine receptors
RJ Lukas, M Bencherif - International review of neurobiology, 1992 - Elsevier
Publisher Summary This chapter focuses on nicotinic acetylcholine receptors (nAChRs).
This component emphasizes studies done using mammalian tissues or their derivatives, and …
This component emphasizes studies done using mammalian tissues or their derivatives, and …
Positive allosteric modulation of the α7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 …
D Bertrand, S Bertrand, S Cassar, E Gubbins, J Li… - Molecular …, 2008 - ASPET
The α7 nicotinic acetylcholine receptor (nAChR), a homopentameric, rapidly activating and
desensitizing ligand-gated ion channel with relatively high degree of calcium permeability, is …
desensitizing ligand-gated ion channel with relatively high degree of calcium permeability, is …
Neuronal nicotinic receptors in synaptic functions in humans and rats: physiological and clinical relevance
EX Albuquerque, EFR Pereira, A Mike… - Behavioural brain …, 2000 - Elsevier
The present report describes the participation of nicotinic receptors (nAChRs) in controlling
the excitability of local neuronal circuitries in the rat hippocampus and in the human cerebral …
the excitability of local neuronal circuitries in the rat hippocampus and in the human cerebral …
Nicotinic acetylcholine receptors and the regulation of neuronal signalling
F Dajas-Bailador, S Wonnacott - Trends in pharmacological sciences, 2004 - cell.com
Neuronal nicotinic acetylcholine (nACh) receptors in the brain are more commonly
associated with modulatory events than mediation of synaptic transmission. nACh receptors …
associated with modulatory events than mediation of synaptic transmission. nACh receptors …
Cholinergic nicotinic receptors: competitive ligands, allosteric modulators, and their potential applications.
MN Romanelli, F Gualtieri - Medicinal research reviews, 2003 - europepmc.org
Discovery of the important role played by nicotinic acetylcholine receptors (nAChRs) in
several CNS disorders has called attention to these membrane proteins and to ligands able …
several CNS disorders has called attention to these membrane proteins and to ligands able …