Nicotinic acetylcholine receptors (nAChRs) display a broad variety of subtypes, which in turn
present a complex subcellular and regional expression pattern in the brain, as well as a …

Although much is known about the functional expression of the neuronal nicotinic
acetylcholine receptors (nAChRs) in various neuronal populations in the brain and …

Nicotinic acetylcholine receptors (nAChRs) are ligand‐gated pentameric cation channels of
α and β subunits. The α5 subunit, when added to heteromeric complexes, alters …

Activation of neuronal nicotinic acetylcholine receptors (nAChRs) has been shown to
maintain cognitive function following aging or the development of dementia. Nicotine and …

The α4β2 nicotinic acetylcholine receptors (nAChRs), a major subtype in the brain, have
been shown to be modulated by chronic treatment with nicotine. In this study, the regulation …

Advances in our understanding of the structure, function and distribution of nicotinic
acetylcholine receptors in the CNS have provided the impetus for new studies examining the …

Neuronal nicotinic acetylcholine receptors are oligomeric protein complexes whose
component subunits are each encoded by a family of homologous genes. The current …

While it has long been documented that nicotine contained in tobacco leaves gives rise to
major public health problems it has also been observed that this alkaloid can have …

The cloning and expression of genes encoding for the human neuronal nicotinic
acetylcholine receptors (nAChRs) has opened new possibilities for investigating their …

The nicotinic acetylcholine receptor (nAChR) belongs to a superfamily of pentameric ligand-
gated ion channels involved in many physiologic and pathologic processes. Among …