Serum surfactant protein D is increased in acute and chronic inflammation in mice

M Fujita, JM Shannon, H Ouchi, DR Voelker… - Cytokine, 2005 - Elsevier
Surfactant protein A (SP-A) and surfactant protein D (SP-D) are important components of
innate immunity that can modify the inflammatory response. However, alterations and …

SP-D-deficient mice are resistant to hyperoxia

D Jain, E Atochina-Vasserman… - … of Physiology-Lung …, 2007 - journals.physiology.org
Surfactant protein D (SP-D), a member of the collectin superfamily, modulates pulmonary
inflammatory responses and innate immunity. Disruption of the SP-D gene in mice induces …

Surfactant protein D protects against acute hyperoxic lung injury

D Jain, EN Atochina-Vasserman, Y Tomer… - American journal of …, 2008 - atsjournals.org
Rationale: Surfactant protein D (SP-D) is a member of the collectin family of soluble, innate,
host defense molecules with demonstrated immunomodulatory properties in vitro …

Alveolar surfactant protein D content modulates bleomycin-induced lung injury

J Casey, J Kaplan, EN Atochina-Vasserman… - American journal of …, 2005 - atsjournals.org
Rationale: Surfactant protein D (SP-D) is a collectin family member with demonstrated
immunomodulatory properties in vitro. We hypothesized that SP-D modulates inflammation …

[HTML][HTML] Surfactant protein A and surfactant protein D variation in pulmonary disease

GL Sorensen, S Husby, U Holmskov - Immunobiology, 2007 - Elsevier
Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

Surfactant protein D deficiency influences allergic immune responses

B Schaub, RM Westlake, H He… - Clinical & …, 2004 - Wiley Online Library
Background The collectin surfactant protein D (SP‐D) confers protection against pulmonary
infection and inflammation. Recent data suggest a role for SP‐D in the modulation of allergic …

Pulmonary surfactant protein D binds MD-2 through the carbohydrate recognition domain

X Nie, C Nishitani, M Yamazoe, S Ariki… - Biochemistry, 2008 - ACS Publications
Pulmonary surfactant protein D (SP-D) is a member of the collectin family and plays crucial
roles in the innate immunity of the lung. We have previously shown that surfactant protein A …

SP‐D and regulation of the pulmonary innate immune system in allergic airway changes

LR Forbes, A Haczku - Clinical & Experimental Allergy, 2010 - Wiley Online Library
The airway mucosal surfaces are constantly exposed to inhaled particles that can be
potentially toxic, infectious or allergenic and should elicit inflammatory changes. The …

Surfactant protein D augments bacterial association but attenuates major histocompatibility complex class II presentation of bacterial antigens

S Hansen, B Lo, K Evans, P Neophytou… - American journal of …, 2007 - atsjournals.org
Surfactant protein D (SP-D) is a secreted pattern recognition molecule associated with lung
surfactant and mediates the clearance of pathogens in multiple ways. SP-D is an …

Lung surfactant proteins involved in innate immunity

P Eggleton, KBM Reid - Current opinion in immunology, 1999 - Elsevier
The two lung surfactant collectins, surfactant protein (SP)-A and SP-D, are involved in host
defence against infectious and allergenic agents via enhancement of killing and clearance …