Pulmonary surfactant protein-D (SP-D) is a soluble collagenous C-type lectin with important
anti-microbial and anti-inflammatory properties. Although it is subject to functionally relevant …

The collectin surfactant protein D (SP-D) is an important component of the pulmonary innate
immune system, but SP-D is also present on extrapulmonary epithelial surfaces and in …

Rationale: Surfactant protein D (SP-D), a 43-kD collectin, is synthesized and secreted by
airway epithelia as a dodecamer formed by assembly of four trimeric subunits. We have …

Background: There is a paucity of lung specific biomarkers to diagnose exacerbations of
chronic obstructive pulmonary disease (COPD) and to track their progression. Surfactant …

Although the lipoprotein complex of pulmonary surfactant has long been recognized as
essential for reducing lung surface tension, its role in lung immune host defense has only …

Surfactant protein‐D (SP‐D) is a member of the collectin family of collagenous proteins with
lectin activity. SP‐D is expressed in numerous tissues, primarily in type II alveolar cells in the …

Pulmonary surfactant, a lipoprotein complex, maintains alveolar integrity and plays an
important role in lung host defense, and control of inflammation. Altered inflammatory …

Abstract Surfactant protein-D (SP-D) is a collectin produced in the distal lung airspaces that
is believed to play an important role in innate pulmonary immunity. Naive immunologic …

Recent studies strongly suggest that surfactant protein D (SP-D) plays important roles in
pulmonary host defense and the regulation of immune and inflammatory reactions in the …

Surfactant Protein D (SP-D) plays important roles in antimicrobial host defense, inflammatory
and immune regulation, and pulmonary surfactant homeostasis. The best-characterized …