BACKGROUND: Surfactant protein (SP) D shares target cells with the proinflammatory
cytokine TNF-α, an important autocrine stimulator of dendritic cells and macrophages in the …

It has become increasingly evident that pulmonary surfactant proteins, SP-A and SP-D,
present in the alveolar and bronchial epithelial fluid linings, not only play significant …

Abstract Surfactant proteins A (SP-A) and D (SP-D) are established as essential components
of our innate immune system for protecting the lung from pathogens and allergens. They …

Components of the airspace-lining material may contribute to the local regulation of immune
function within the lung. We report here that recombinant rat pulmonary surfactant …

Surfactant protein D (SP-D) is an oligomeric calcium-dependent lectin with important roles in
innate host defence against infectious microorganisms. Several studies have shown that …

The lung is repeatedly exposed to inhaled particles and pathogens that are cleared by the
actions of a multi-component innate host defense system. The pulmonary collectins …

Biological markers can help to better identify a disease or refine its diagnosis. In the present
study, the association between surfactant protein D (SP‑D) and chronic obstructive …

Surfactant proteins A (SP-A) and D (SP-D) are lung collectins that are constituents of the
innate immune system of the lung. Recent evidence (Sano, H., Sohma, H., Muta, T., Nomura …

Surfactant protein (SP) D functions as a soluble pattern recognition molecule to mediate the
clearance of pathogens by phagocytes in the innate immune response. We hypothesize that …

Background: Surfactant protein-D (SFTPD) is a component of the lung innate immunity that
enhances clearance of pathogens and modulates inflammatory responses. An inverse …