The lung surfactant proteins (SP) A and D are large multimeric proteins and belong to a
family of collagenous C-type lectins designated collectins. Both SP-A and SP-D are believed …

Surfactant protein D (SP-D) plays an important role in lung host defence. SP-D levels have
been shown to be depleted in cystic fibrosis (CF) patients. A recombinant fragment of the …

Surfactant protein (SP)-D is a lung-derived protein that has been proposed as a biomarker
for inflammatory lung disease. Serum SP-D was evaluated as a biomarker for components of …

Summary Background Surfactant protein D (SP‐D), a secreted pattern recognition molecule
associated with pulmonary innate immunity, has been shown to mediate the clearance of …

Surfactant protein A (SP-A) is an innate immune molecule that regulates pathogen
clearance and lung inflammation. SP-A modulates innate immune functions such as …

Abstract Surfactant protein-D (SP-D) participates in the innate response to inhaled
microorganisms and organic antigens, and contributes to immune and inflammatory …

Alveolar type II cells secrete, internalize, and recycle pulmonary surfactant, a lipid and
protein complex that increases alveolar compliance and participates in pulmonary host …

Because the lungs function as the body's gas-exchange organ, they are inevitably exposed
to air that is contaminated with pathogens, allergens and pollutants. Host-defence …

Pulmonary surfactant protein-D (SP-D) is a member of the collectin family of C-type lectins
that is synthesized in many tissues including respiratory epithelial cells in the lung. SP-D is …

Surfactant protein D (SFTPD) induces emphysema in knockout mice, but the association of
SFTPD with chronic obstructive pulmonary disease (COPD) and emphysema in humans is …