The surfactant-associated proteins SP-A and D are pattern recognition molecules with
collectin structure. A single nucleotide polymorphism (SNP) exchanging a methionine (Met) …

The collectin surfactant protein (SP)-A has been implicated in multiple immunoregulatory
functions of innate pulmonary host defense via modulating immune responses both in vitro …

Pulmonary surfactant protein-D (SP-D) is a multifunctional, pattern recognition molecule
involved in resistance to allergen challenge and pulmonary inflammation. In view of …

Surfactant protein D (SP-D) plays an important role in lung host defence. SP-D levels have
been shown to be depleted in cystic fibrosis (CF) patients. A recombinant fragment of the …

Surfactant proteins, SP-A and SP-D, are collagen-containing C-type (calcium dependent)
lectins called collectins, which contribute significantly to surfactant homeostasis and …

Summary Background Surfactant protein D (SP‐D), a secreted pattern recognition molecule
associated with pulmonary innate immunity, has been shown to mediate the clearance of …

Surfactant-associated protein D (SP-D) is a collectin that is present in lung surfactant and
mucosal surfaces. Although SP-D regulates diverse functions, only a few proteins are known …

The lung surfactant proteins (SP) A and D are large multimeric proteins and belong to a
family of collagenous C-type lectins designated collectins. Both SP-A and SP-D are believed …

Surfactant protein D (SP-D) is a constituent of the innate immune system that plays a role in
the host defense against lung pathogens and in modulating inflammatory responses. While …

Surfactant protein A (SP-A) is an innate immune molecule that regulates pathogen
clearance and lung inflammation. SP-A modulates innate immune functions such as …