Because the lungs function as the body's gas-exchange organ, they are inevitably exposed
to air that is contaminated with pathogens, allergens and pollutants. Host-defence …

Lung surfactant protein (SP)-D belongs to the family of soluble collagenous C-type lectins,
named collectins. SP-D participates in the local innate immune defense of the lung, eliciting …

Surfactant protein D (SP-D) plays diverse and important roles in innate immunity and
pulmonary homeostasis. Neutrophils and myeloperoxidase (MPO) colocalized with SP-D in …

Surfactant protein D (SFTPD) induces emphysema in knockout mice, but the association of
SFTPD with chronic obstructive pulmonary disease (COPD) and emphysema in humans is …

Abstract Background Ozone (O 3), a common air pollutant, induces exacerbation of asthma
and chronic obstructive pulmonary disease. Pulmonary surfactant protein (SP)-D modulates …

Abstract Surfactant protein D (SP-D) is a molecule of the innate immune system that
recognizes the patterns of surface carbohydrate on pathogens and targets them for …

Surfactant protein D (SP-D) is one of two collectins found in the pulmonary alveolus. On the
basis of homology with other collectins, potential functions for SP-D include roles in innate …

Rapid removal of apoptotic cells is an important mechanism for immune homeostasis and
the resolution of inflammation. Delayed clearance of apoptotic alveolar macrophages may …

Alveolar type II cells secrete, internalize, and recycle pulmonary surfactant, a lipid and
protein complex that increases alveolar compliance and participates in pulmonary host …

Pulmonary surfactant protein-D (SP-D) is a member of the collectin family of C-type lectins
that is synthesized in many tissues including respiratory epithelial cells in the lung. SP-D is …