Acute myeloid leukemia: biologic, prognostic, and therapeutic insights

S Khaled, M Al Malki, G Marcucci - Oncology, 2016 - go.gale.com
Acute myeloid leukemia (AML) is a biologically complex and molecularly and clinically
heterogeneous disease, and its incidence is increasing as the population ages …

Current and emerging molecular and epigenetic disease entities in acute myeloid leukemia and a critical assessment of their therapeutic modalities

X Zhao, H Liu, LN Wang, L Yang, X Liu - Seminars in Cancer Biology, 2022 - Elsevier
Acute myeloid leukemia (AML) is the most frequently diagnosed acute leukemia, and its
incidence increases with age. Although the etiology of AML remains unknown, exposure to …

[HTML][HTML] Molecular landscape of acute myeloid leukemia: prognostic and therapeutic implications

L Marando, BJP Huntly - Current oncology reports, 2020 - Springer
Abstract Purpose of Review The field of acute myeloid leukemia (AML) has been
revolutionized in recent years by the advent of high-throughput techniques, such as next …

New strategies in acute myeloid leukemia: redefining prognostic markers to guide therapy

I Khan, JK Altman, JD Licht - Clinical Cancer Research, 2012 - AACR
Although standard therapy for AML has been relatively constant over the past 2 decades,
this may be changing with enhanced technologies allowing for the classification of acute …

New prognostic markers in acute myeloid leukemia: perspective from the clinic

JM Foran - Hematology 2010, the American Society of …, 2010 - ashpublications.org
Acute myeloid leukemia (AML) is a disease with marked heterogeneity in both response to
therapy and survival. Cytogenetics, age, and performance status have long determined …

Acute myeloid leukemia: from mutation profiling to treatment decisions

C DiNardo, C Lachowiez - Current hematologic malignancy reports, 2019 - Springer
Abstract Purpose of Review Awareness of the molecular landscape of AML has improved
AML care over the last 5 years. This review summarizes updates regarding the diagnostic …

[HTML][HTML] The clinical impact of the molecular landscape of acute myeloid leukemia

S Kayser, MJ Levis - Haematologica, 2023 - ncbi.nlm.nih.gov
Research into the underlying pathogenic mechanisms of acute myeloid leukemia (AML) has
led to remarkable advances in our understanding of the disease. Mutations now allow us to …

Molecular characterization of acute myeloid leukemia and its impact on treatment

O Frankfurt, JD Licht, MS Tallman - Current opinion in Oncology, 2007 - journals.lww.com
Molecular characterization of acute myeloid leukemia and its... : Current Opinion in Oncology
Molecular characterization of acute myeloid leukemia and its impact on treatment : Current …

Acute myelogenous leukemia: current treatment and future directions

DM Mastrianni, NM Tung, DG Tenen - The American journal of medicine, 1992 - Elsevier
Acute myelogenous leukemia (AML), although an uncommon disorder, is a useful prototype
for the treatment of malignancies in general. Significant advances have been made in both …

[PDF][PDF] Acute myeloid leukemia: a review

A Pelcovits, R Niroula - Rhode Island medical journal, 2020 - rimed.org
Acute myeloid leukemia (AML) is a malignancy of the stem cell precursors of the myeloid
lineage (red blood cells, platelets, and white blood cells other than B and T cells). Like other …