Using novel computed tomography analysis to describe the contribution and distribution of emphysema and small airways disease in chronic obstructive pulmonary …

K Ostridge, K Gove, KHW Paas, H Burke… - Annals of the …, 2019 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation, caused by emphysema and small airways disease (SAD). Computed tomography …

Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory …

G Vande Velde, J Poelmans… - Disease models & …, 2016 - journals.biologists.com
In vivo lung micro-computed tomography (micro-CT) is being increasingly embraced in
pulmonary research because it provides longitudinal information on dynamic disease …

Experimental and quantitative imaging techniques in interstitial lung disease

ND Weatherley, JA Eaden, NJ Stewart, BJ Bartholmai… - Thorax, 2019 - thorax.bmj.com
Interstitial lung diseases (ILDs) are a heterogeneous group of conditions, with a wide and
complex variety of imaging features. Difficulty in monitoring, treating and exploring novel …

Quantitative computed tomography in chronic obstructive pulmonary disease

DA Lynch, MA Al-Qaisi - Journal of thoracic imaging, 2013 - journals.lww.com
Quantitative computed tomography is being increasingly used to quantify the features of
chronic obstructive pulmonary disease, specifically emphysema, air trapping, and airway …

Quantitative computed tomography of lung parenchyma in chronic obstructive pulmonary disease: an overview

JD Newell Jr - Proceedings of the American Thoracic Society, 2008 - atsjournals.org
This article provides a brief overview of the important issues influencing the effective use of
quantitative X-ray computed tomography (QCT) in the assessment of the lung parenchyma …

[HTML][HTML] Quantification of heterogeneity in lung disease with image-based pulmonary function testing

CS Stahr, CR Samarage, M Donnelley, N Farrow… - Scientific reports, 2016 - nature.com
Computed tomography (CT) and spirometry are the mainstays of clinical pulmonary
assessment. Spirometry is effort dependent and only provides a single global measure that …

A mixed phenotype of airway wall thickening and emphysema is associated with dyspnea and hospitalization for chronic obstructive pulmonary disease

N Van Tho, E Ogawa, LTH Trang, Y Ryujin… - Annals of the …, 2015 - atsjournals.org
Rationale: Quantitative computed tomography (CT) has been used to phenotype patients
with chronic obstructive pulmonary disease (COPD). A mixed phenotype is defined as the …

Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function1

EA Hoffman, JM Reinhardt, M Sonka, BA Simon… - Academic radiology, 2003 - Elsevier
Rationale and Objectives. Efforts to establish a quantitative approach to the computed
tomography (CT)-based characterization of the lung parenchyma in interstitial lung disease …

Dysfunctional lung anatomy and small airways degeneration in COPD

C Martin, J Frija, PR Burgel - International journal of chronic …, 2013 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is characterized by incompletely reversible
airflow obstruction. Direct measurement of airways resistance using invasive techniques has …

[HTML][HTML] The role of CT scanning in multidimensional phenotyping of COPD

M Bafadhel, I Umar, S Gupta, JV Raj, DD Vara… - Chest, 2011 - Elsevier
Background COPD is a heterogeneous disease characterized by airflow obstruction and
diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in …