Chronic obstructive pulmonary disease (COPD) exacerbations have a major impact on
patients with COPD, yet they are complex events that are associated with a number of …

BACKGROUND: COPD patients have varying degrees of airways disease and emphysema.
CT scanning can differentiate these pathological subtypes. We evaluated airway dimensions …

Objectives A combination of functional measurements reflecting a decrease in maximum
flow, a degree of lung hyperinflation, the relationship between maximum inspiratory and …

In patients with pulmonary emphysema, emphysematous changes are not uniform and vary
from minimum alveolar destruction to advanced bullous formation, depending on the lobe or …

RATIONALE AND OBJECTIVES: Although multiple detector computed tomography (MDCT)
and hyperpolarized gas magnetic resonance imaging (HP MRI) have demonstrated ability to …

Rationale: The decades-long progression of chronic obstructive pulmonary disease (COPD)
renders identifying different trajectories of disease progression challenging. Objectives: To …

Background: Considerable research has been conducted into the nature of airway
inflammation in chronic obstructive pulmonary disease (COPD) but the relationship between …

Study objectives We determined whether emphysema demonstrated on high-resolution CT
(HRCT) scanning in apparently well smokers is associated with airflow obstruction …

Objectives Chronic obstructive pulmonary disease (COPD) is characterized by variable
contributions of emphysema and airway disease on computed tomography (CT), and still …

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation caused by small airways increased resistance and/or terminal airspaces …