Platelets in host defense: experimental and clinical insights
Platelets are central players in thrombosis and hemostasis but are increasingly recognized
as key components of the immune system. They shape ensuing immune responses by …
as key components of the immune system. They shape ensuing immune responses by …
The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases
L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
Nouvelle cuisine: platelets served with inflammation
Platelets are small cellular fragments with the primary physiological role of maintaining
hemostasis. In addition to this well-described classical function, it is becoming increasingly …
hemostasis. In addition to this well-described classical function, it is becoming increasingly …
Platelets as central mediators of systemic inflammatory responses
TL Smith, AS Weyrich - Thrombosis research, 2011 - Elsevier
Systemic inflammatory responses are associated with high morbidity and mortality and
represent a diverse and clinically challenging group of diseases. Platelets are increasingly …
represent a diverse and clinically challenging group of diseases. Platelets are increasingly …
Platelets as immune mediators: their role in host defense responses and sepsis
Platelets occupy a central role at the interface between thrombosis and inflammation. At
sites of vascular damage, adherent platelets physically and functionally interact with …
sites of vascular damage, adherent platelets physically and functionally interact with …
Role of platelets in detection and regulation of infection
I Portier, RA Campbell - Arteriosclerosis, thrombosis, and vascular …, 2021 - Am Heart Assoc
Platelets are classically known as essential mediators of hemostasis and thrombosis.
However, in recent years, platelets have gained recognition for their inflammatory functions …
However, in recent years, platelets have gained recognition for their inflammatory functions …
Platelets: signaling cells in the immune continuum
AS Weyrich, GA Zimmerman - Trends in immunology, 2004 - cell.com
Platelets have intricate signaling mechanisms and participate in a breadth of cellular
interactions. This diversity is frequently unrecognized. In addition to being the chief cellular …
interactions. This diversity is frequently unrecognized. In addition to being the chief cellular …
Emerging evidence for platelets as immune and inflammatory effector cells
MT Rondina, O Garraud - Frontiers in immunology, 2014 - frontiersin.org
While traditionally recognized for their roles in hemostatic pathways, emerging evidence
demonstrates that platelets have previously unrecognized, dynamic roles that span the …
demonstrates that platelets have previously unrecognized, dynamic roles that span the …
Platelets and innate immunity
JW Semple, J Freedman - Cellular and Molecular Life Sciences, 2010 - Springer
Although platelets are best known as primary mediators of hemostasis, this function
intimately associates them with inflammatory processes, and it has been increasingly …
intimately associates them with inflammatory processes, and it has been increasingly …
Blood platelets in infection: the multiple roles of the platelet signalling machinery
SMG Trivigno, GF Guidetti, SS Barbieri… - International Journal of …, 2023 - mdpi.com
Platelets are classically recognized for their important role in hemostasis and thrombosis but
they are also involved in many other physiological and pathophysiological processes …
they are also involved in many other physiological and pathophysiological processes …