Direct interaction between endothelial nitric-oxide synthase and dynamin-2: implications for nitric-oxide synthase function
S Cao, J Yao, TJ McCabe, Q Yao, ZS Katusic… - Journal of Biological …, 2001 - ASBMB
Endothelial nitric-oxide synthase (eNOS) is regulated in part through specific protein
interactions. Dynamin-2 is a large GTPase residing within similar membrane compartments …
interactions. Dynamin-2 is a large GTPase residing within similar membrane compartments …
The proline-rich domain of dynamin-2 is responsible for dynamin-dependent in vitro potentiation of endothelial nitric-oxide synthase activity via selective effects on …
S Cao, J Yao, V Shah - Journal of Biological Chemistry, 2003 - ASBMB
The GTPase dynamin-2 (dyn-2) binds and positively regulates the nitric oxide-generating
enzyme, endothelial nitric-oxide synthase (eNOS)(Cao, S., Yao, Y., McCabe, T., Yao, Q …
enzyme, endothelial nitric-oxide synthase (eNOS)(Cao, S., Yao, Y., McCabe, T., Yao, Q …
Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2
N Kang-Decker, S Cao, S Chatterjee… - Journal of cell …, 2007 - journals.biologists.com
Endothelial cell-based angiogenesis requires activation of survival signals that generate
resistance to external apoptotic stimuli, such as tumor necrosis factor-alpha (TNF-α), during …
resistance to external apoptotic stimuli, such as tumor necrosis factor-alpha (TNF-α), during …
Regulation of endothelial nitric oxide synthase activity by protein-protein interaction
Y Su - Current pharmaceutical design, 2014 - ingentaconnect.com
Endothelial nitric oxide synthase (eNOS) is expressed in vascular endothelial cells and
plays an important role in the regulation of vascular tone, platelet aggregation and …
plays an important role in the regulation of vascular tone, platelet aggregation and …
Nitric oxide regulation of protein trafficking in the cardiovascular system
CJ Lowenstein - Cardiovascular research, 2007 - academic.oup.com
Nitric oxide (NO) is a second messenger with diverse roles in the cardiovascular system,
such as inhibiting thrombosis and limiting vascular inflammation. One mechanism by which …
such as inhibiting thrombosis and limiting vascular inflammation. One mechanism by which …
Oligomerization of endothelial nitric oxide synthase: Evidence for a dominant negative effect of truncation mutants
CM Lee, LJ Robinson, T Michel - Journal of Biological Chemistry, 1995 - ASBMB
Nitric oxide produced by the endothelial isoform of nitric oxide synthase (ecNOS) is a key
determinant of vascular tone. In contrast to other nitric oxide synthase (NOS) isoforms, which …
determinant of vascular tone. In contrast to other nitric oxide synthase (NOS) isoforms, which …
The Golgi Association of Endothelial Nitric Oxide Synthase Is Necessary for the Efficient Synthesis of Nitric Oxide (∗)
WC Sessa, G Garca-Cardea, J Liu, A Keh… - Journal of Biological …, 1995 - ASBMB
The particulate enzyme, endothelial nitric oxide synthase (eNOS), produces nitric oxide to
maintain normal vasodilator tone in blood vessels. In this study, we demonstrate that eNOS …
maintain normal vasodilator tone in blood vessels. In this study, we demonstrate that eNOS …
Role of endothelial nitric oxide synthase in endothelial cell migration
T Murohara, B Witzenbichler… - … , and vascular biology, 1999 - Am Heart Assoc
Endothelium-derived nitric oxide (NO) and its precursor l-arginine have been implied to
promote angiogenesis, but little is known about the precise mechanism. The inhibition of …
promote angiogenesis, but little is known about the precise mechanism. The inhibition of …
Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase
E Gonzalez, R Kou, AJ Lin, DE Golan… - Journal of Biological …, 2002 - ASBMB
The endothelial isoform of nitric-oxide synthase (eNOS) undergoes a complex pattern of
covalent modifications, including acylation with the fatty acids myristate and palmitate as …
covalent modifications, including acylation with the fatty acids myristate and palmitate as …
Actin cytoskeleton organization and posttranscriptional regulation of endothelial nitric oxide synthase during cell growth
CD Searles, L Ide, ME Davis, H Cai… - Circulation research, 2004 - Am Heart Assoc
Posttranscriptional regulation of endothelial nitric oxide synthase (eNOS) expression is an
important mechanism by which endothelial cells respond to various physiological and …
important mechanism by which endothelial cells respond to various physiological and …