Objective: The study aimed to evaluate the preventive effects of hydroxycitric acid (HCA) for
stone formation in the glyoxylate-induced mouse model. Materials and Methods: Male …

Objective: To explore the theraputic effects and potential mechanisms of hydrogen-rich
water (HRW) against oxalate-induced kidney injury. Methods: The mouse model of Calcium …

Kidney stone is a urinary system disease with a high incidence, and effective stone drugs
are limited. Hydroxycitric acid (HCA), mainly found in Garcinia cambogia and Hibiscus …

Nephrolithiasis is a common and frequently-occurring disease in the urinary system with
high recurrence. The present study aimed to explore the protective effect and underlying …

Background High prevalence and reoccurrence rate of nephrolithiasis bring about serious
socioeconomic and healthcare burden, necessitating the need of effective therapeutic …

Objectives: To clarify the role of renal tubular cell (RTC) injury and oxidative stress in the
early stage of renal calcium oxalate crystal formation in a mouse model. Methods: Daily intra …

This study investigates the mechanism by which butyric acid can protect against calcium
oxalate (CaOx) nephrolithiasis. To do so, a rat model was used with 0.75% ethylene glycol …

Ursolic acid (UA) has been proved to have antioxidant and anti-inflammatory effects.
However, it is not clear whether it has a protective impact on kidney damage induced by …

Background and objective Renal tissue injuries by free radicals are an essential reason in
pathogenesis of urinary tract stones. Ethylene glycol is one of the toxic agents which can …

Background. Kidney stone disease induces chronic renal insufficiency by crystal‐induced
renal tubular epithelial cell injury. It has been reported that the prevalence of kidney stone …