The successful treatment of patients with osteosarcoma requires close cooperation within an
experienced multidisciplinary team including pediatric or medical oncologists, surgeons …

Osteosarcoma is a malignant tumor that primarily affects the long bones but can also involve
other bones in the body. It has a bimodal distribution with peaks in the second decade of life …

Despite significant advancements in the diagnosis and treatment of osteosarcoma to date,
overall survival has remained relatively constant for over 2 decades. The challenge in …

Osteosarcoma is a primary malignancy of bone with a high tendency to metastasize.
Although it can occur at any age, osteosarcoma has a peak incidence in the second decade …

We aimed to evaluate the prognostic significance of traditional clinical predictors in
osteosarcoma through an international collaboration of 10 teams of investigators (2680 …

Background The purpose of this study was to analyze improvements in overall survival over
21 years (1982–2002), with a 5-year minimum follow-up, in the largest series from a single …

Objectives: Summarize the pathophysiology of primary and secondary forms of
osteosarcoma. Identify the typical imaging findings associated with osteosarcoma. Review …

Opinion statement Patients with suspected or confirmed osteosarcoma should be evaluated
and treated at a comprehensive cancer center within a multidisciplinary sarcoma program …

Major advances have been achieved in the treatment of osteosarcoma with the discovery of
several chemotherapeutic agents that were active in the disease. These agents comprise …

The treatment of osteosarcoma requires a multidisciplinary approach involving the family
physician, orthopedic oncologist, medical oncologist, radiologist and pathologist …