Enhanced plasma ghrelin levels in rats with streptozotocin‐induced diabetes

T Masaoka, H Suzuki, H Hosoda, T Ota… - FEBS …, 2003 - Wiley Online Library
Ghrelin is a novel gastrointestinal peptide that stimulates growth hormone secretion, food
intake, and body weight gain. Increased ghrelin secretion has been reported in such …

Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion

T Shiiya, M Nakazato, M Mizuta, Y Date… - The Journal of …, 2002 - academic.oup.com
Ghrelin, a novel GH-releasing peptide isolated from human and rat stomach, stimulates food
intake and GH secretion. We determined plasma ghrelin concentrations in patients with …

Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration

K Toshinai, MS Mondal, M Nakazato, Y Date… - Biochemical and …, 2001 - Elsevier
Ghrelin is a novel gut–brain peptide that binds to the growth hormone secretagogue
receptor (GHS-R), thereby functioning in the regulation of growth hormone (GH) release and …

Changes in ghrelin and ghrelin receptor expression according to feeding status

MS Kim, CY Yoon, KH Park, CS Shin, KS Park… - …, 2003 - journals.lww.com
Ghrelin, a newly identified gut hormone, has been implicated in the regulation of food intake
and energy homeostasis. This study was undertaken to investigate changes in expression …

Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans

H Ariyasu, K Takaya, T Tagami, Y Ogawa… - The Journal of …, 2001 - academic.oup.com
Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat
stomach and is involved in a novel system for regulating GH release. Although previous …

Ghrelin causes hyperphagia and obesity in rats

AM Wren, CJ Small, CR Abbott, WS Dhillo, LJ Seal… - Diabetes, 2001 - Am Diabetes Assoc
Ghrelin, a circulating growth hormone–releasing peptide derived from the stomach,
stimulates food intake. The lowest systemically effective orexigenic dose of ghrelin was …

Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose

E Nakagawa, N Nagaya, H Okumura… - Clinical …, 2002 - portlandpress.com
Ghrelin is a novel growth hormone (GH)-releasing peptide, isolated from the stomach, which
may also cause a positive energy balance by stimulating food intake and reducing fat …

Role of ghrelin in streptozotocin-induced diabetic hyperphagia

S Ishii, J Kamegai, H Tamura, T Shimizu… - …, 2002 - academic.oup.com
Ghrelin, an endogenous ligand for the growth hormone (GH) secretagogue receptor, was
originally purified from the rat stomach. We have previously reported that central …

Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach

SG Moesgaard, B Ahrén, RD Carr, DX Gram… - Regulatory peptides, 2004 - Elsevier
Ghrelin is a peptide identified as an endogenous ligand for the growth hormone
secretagogue receptor. Studies have shown that ghrelin stimulates growth hormone …

Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations

HM Lee, G Wang, EW Englander, M Kojima… - …, 2002 - academic.oup.com
Ghrelin, an endogenous ligand for the GH secretagogue receptor was characterized
recently from extracts of rat stomach. We describe the enteric distribution of ghrelin …