MHC-NP: predicting peptides naturally processed by the MHC
We present MHC-NP, a tool for predicting peptides naturally processed by the MHC
pathway. The method was part of the 2nd Machine Learning Competition in Immunology …
pathway. The method was part of the 2nd Machine Learning Competition in Immunology …
NetCleave: an open-source algorithm for predicting C-terminal antigen processing for MHC-I and MHC-II
P Amengual-Rigo, V Guallar - Scientific reports, 2021 - nature.com
Antigens presented on the cell surface have been subjected to multiple biological
processes. Among them, C-terminal antigen processing constitutes one of the main …
processes. Among them, C-terminal antigen processing constitutes one of the main …
Machine learning competition in immunology–Prediction of HLA class I binding peptides
Experimental studies of immune system and related applications such as characterization of
immune responses against pathogens, vaccine design, or optimization of therapies are …
immune responses against pathogens, vaccine design, or optimization of therapies are …
[HTML][HTML] Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule
M Rasmussen, M Harndahl, A Stryhn… - The Journal of …, 2014 - journals.aai.org
Abstract MHC class I molecules (HLA-I in humans) present peptides derived from
endogenous proteins to CTLs. Whereas the peptide-binding specificities of HLA-A and-B …
endogenous proteins to CTLs. Whereas the peptide-binding specificities of HLA-A and-B …
NIEluter: Predicting peptides eluted from HLA class I molecules
The immune system has evolved to make a diverse repertoire of peptides processed from
self and foreign proteomes, which are displayed in antigen-binding grooves of major …
self and foreign proteomes, which are displayed in antigen-binding grooves of major …
Unveiling the peptide motifs of HLA-C and HLA-G from naturally presented peptides and generation of binding prediction matrices
M Di Marco, H Schuster, L Backert… - The Journal of …, 2017 - journals.aai.org
The classical HLA-C and the nonclassical HLA-E and HLA-G molecules play important roles
both in the innate and adaptive immune system. Starting already during embryogenesis and …
both in the innate and adaptive immune system. Starting already during embryogenesis and …
Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan
CD4 positive T helper cells control many aspects of specific immunity. These cells are
specific for peptides derived from protein antigens and presented by molecules of the …
specific for peptides derived from protein antigens and presented by molecules of the …
In Silico Tools for Predicting Peptides Binding to HLA-Class II Molecules: More Confusion than Conclusion
U Gowthaman, JN Agrewala - Journal of proteome research, 2008 - ACS Publications
Identification of promiscuous peptides, which bind to human leukocyte antigen, is
indispensable for global vaccination. However, the development of such vaccines is …
indispensable for global vaccination. However, the development of such vaccines is …
NetMHCpan, a Method for Quantitative Predictions of Peptide Binding to Any HLA-A and -B Locus Protein of Known Sequence
Background Binding of peptides to Major Histocompatibility Complex (MHC) molecules is
the single most selective step in the recognition of pathogens by the cellular immune system …
the single most selective step in the recognition of pathogens by the cellular immune system …
NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ
Major histocompatibility complex class II (MHCII) molecules play an important role in cell-
mediated immunity. They present specific peptides derived from endosomal proteins for …
mediated immunity. They present specific peptides derived from endosomal proteins for …