Infectious diseases are among the major health issues of the 21st century. The substantial
use of antibiotics over the years has contributed to the dissemination of multidrug resistant …

Based on the recent reports of World Health Organization, increased antibiotic resistance
prevalence among bacteria represents the greatest challenge to human health. In addition …

Infectious diseases constitute an increasing threat to public health and medical systems
worldwide. Particularly, the emergence of multidrug-resistant pathogens has left the …

Despite the fact that we live in an era of advanced and innovative technologies for
elucidating underlying mechanisms of diseases and molecularly designing new drugs …

Introduction: Despite extensive advances in the production and synthesis of antibiotics,
infectious diseases are one of the main problems of the 21st century due to multidrug …

Antibiotic resistance has become a threat to microbial therapies nowadays. The
conventional approaches possess several limitations to combat microbial infections …

Despite the wide success of antibiotics, the treatment of bacterial infections still faces
significant challenges, particularly the emergence of antibiotic resistance. As a result …

In the field of antibiotherapy, intracellular infections remain difficult to eradicate mainly due to
the poor intracellular penetration of most of the commonly used antibiotics. Bacteria have …

Current drug therapy against infections is threatening to become obsolete due to the poor
physical, chemical, biological and pharmacokinetic properties of drugs, followed by high risk …

Despite the fact that many new drugs and technologies have been developed to combat the
infectious diseases, these have continued to be global health challenges. The use of …