Autophagy is a conserved catabolic process that delivers the cytosol and cytosolic
constituents to the lysosome. Its fundamental role is to maintain cellular homeostasis and to …

Autophagy is a bulk lysosomal degradation process important in development,
differentiation and cellular homeostasis in multiple organs. Interestingly, neuronal survival is …

Autophagy is a constitutive lysosomal catabolic pathway that degrades damaged organelles
and protein aggregates. Neuronal survival is highly dependent on autophagy due to its post …

The term autophagy encompasses different pathways that route cytoplasmic material to
lysosomes for degradation and includes macroautophagy, chaperone-mediated autophagy …

The autophagy-lysosomal pathway is a major proteolytic pathway that in mammalian
systems mainly comprises of macroautophagy and chaperone-mediated autophagy. The …

Highlights•Autophagy is a lysosomal degradation process essential for neuronal
survival.•Autophagy is a highly compartmentalized process in neurons.•Intercellular …

Although autophagy has frequently been viewed as a cell death mechanism in the
mammalian system, it is now considered as indispensable for the homeostasis of cells …

Autophagy is a conserved pathway that delivers cytoplasmic contents to the lysosome for
degradation. Here we consider its roles in neuronal health and disease. We review …

Neurons have highly dynamic cellular processes for their proper functions such as cell
growth, synaptic formation, or synaptic plasticity by regulating protein synthesis and …

Autophagy is a major degradation pathway where double-membrane vesicles called
autophagosomes deliver cytoplasmic content to the lysosome. Increasing evidence …