Inter-laboratory comparison of chronic myeloid leukemia minimal residual disease monitoring: summary and recommendations

T Zhang, S Grenier, B Nwachukwu, C Wei… - The Journal of Molecular …, 2007 - Elsevier
In patients with chronic myeloid leukemia, the use of real-time quantitative reverse
transcription-polymerase chain reaction (qRT-PCR) for measuring BCR-ABL1 transcripts …

Very low level of major BCR-ABL expression in blood of some healthy individuals.

C Biernaux, A Sels, G Huez… - Bone marrow …, 1996 - europepmc.org
The nested reverse transcriptase polymerase chain reaction (RT-PCR) provides a powerful
tool for detection of minimal residual disease in CML. The RT-PCR used in the present study …

Standardisation of molecular monitoring for chronic myeloid leukaemia

NCP Cross - Best practice & research Clinical haematology, 2009 - Elsevier
Molecular monitoring of chronic myeloid leukaemia (CML) patients by real time quantitative
reverse transcriptase PCR (RQ-PCR) is of clinical value, but the use of diverse laboratory …

Minimal residual disease after bone marrow transplantation for chronic myelogenous leukemia and implications for graft-versus-leukemia effect: A review of recent …

K Miyamura, AJ Barrett, Y Kodera… - Bone Marrow …, 1994 - europepmc.org
Cure of leukemia by allogeneic BMT is achieved by the combined effect of the myeloablative
preparative regimen and an allo-immune response of donor cells to residual leukemia …

Monitoring of residual disease in chronic myelogenous leukemia by quantitative polymerase chain reaction.

T Lion, S Izraeli, T Henn, A Gaiger, W Mor, H Gadner - Leukemia, 1992 - europepmc.org
The polymerase chain reaction (PCR) has become a standard method for highly sensitive
detection of the bcr/abl rearrangement in patients with chronic myelogenous leukemia …

Quantitative determination of the hybrid Bcr‐Abl RNA in patients with chronic myelogenous leukaemia under interferon therapy

MC Malinge, FX Mahon, MH Delfau… - British journal of …, 1992 - Wiley Online Library
In vitro amplification of the Bcr‐Abl cDNA has been widely used to assess for the presence
of minimal residual disease in patients with chronic myelogenous leukaemia (CML) …

Red blood cell phenotyping is a sensitive technique for monitoring chronic myeloid leukaemia patients after T‐cell‐depleted bone marrow transplantation and after …

N Schaap, A Schattenberg, B Bär… - British journal of …, 2000 - Wiley Online Library
Fifteen consecutive patients with Philadelphia chromosome (Ph)‐positive chronic myeloid
leukaemia (CML) who relapsed from T‐cell‐depleted bone marrow transplantation (BMT) …

Polymerase chain reaction-based detection of minimal residual disease in acute lymphoblastic leukemia predicts relapse after allogeneic BMT.

J Radich, P Ladne, T Gooley - … : journal of the American Society for …, 1995 - europepmc.org
We studied 20 patients who had received allogeneic bone marrow transplants for acute
lymphoblastic leukemia. Using the polymerase chain reaction (PCR), we examined them for …

Detection of residual leukaemia more than 10 years after allogeneic bone marrow transplantation for chronic myelogenous leukaemia.

F Van Rhee, F Lin, NC Cross, CD Reid… - Bone marrow …, 1994 - europepmc.org
The clinical status of a homogeneous cohort of long-term survivors of allogeneic marrow
transplantation was assessed and residual leukaemia was studied by reverse transcription …

Quantification of minimal residual disease in patients with BCR‐ABL‐positive acute lymphoblastic leukaemia using quantitative competitive polymerase chain reaction

G Mitterbauer, P Nemeth, S Wacha… - British journal of …, 1999 - Wiley Online Library
We analysed 20 patients with BCR‐ABL‐positive acute lymphoblastic leukaemia (ALL) by
quantitative competitive polymerase chain reaction (QC‐PCR) to study the kinetics of the …