A simple, effective and well‐tolerated treatment regime for West syndrome

E Schlumberger, O Dulac - Developmental Medicine & Child …, 1994 - Wiley Online Library
The authors systematically treated 94 patients with West syndrome using the same protocol
of sodium valproate and steroids, starting with hydrocortisone (HC) orally for two weeks. If …

Medical treatment of West syndrome in Japan

K Watanabe - Journal of Child Neurology, 1995 - journals.sagepub.com
Although corticotropin (ACTH) is still the most effective drug for the treatment of West
syndrome, a variety of other treatment modalities have been tried because of corticotropin's …

Long-term weekly ACTH therapy for relapsed West syndrome

T Okanishi, C Sugiura, Y Saito, Y Maegaki, K Ohno… - Pediatric …, 2008 - Elsevier
Adrenocorticotrophic hormone (ACTH) therapy is an established treatment for West
syndrome. However, some patients may relapse after this therapy, for whom there is no …

Preliminary report of a multi-center study on the West syndrome

R Nolte, HJ Christen, J Doerrer - Brain and Development, 1988 - Elsevier
During a 12-month period, 54 infants with the West syndrome (10 idiopathic, 44
symptomatic) referred to 10 major children's hospitals for initial treatment were evaluated to …

Therapeutic efficacy and adverse effects of adrenocorticotropic hormone therapy in west syndrome: differences in dosage of adrenocorticotropic hormone, onset of …

S Hamano, S Yamashita, M Tanaka, S Yoshinari… - The Journal of …, 2006 - Elsevier
OBJECTIVES: To determine the dosage and factors influencing efficacy of
adrenocorticotropic hormone (ACTH) for West syndrome. STUDY DESIGN: A retrospective …

West syndrome: response to valproate

S Chandra, A Bhave, R Bhargava, C Kumar… - Frontiers in …, 2012 - frontiersin.org
Management of West syndrome is unsatisfactory. In our clinic we observed that a significant
proportion of patients respond to usual dose of valproate. Objective: To prospectively assess …

Liposteroid (dexamethasone palmitate) therapy for West syndrome: a comparative study with ACTH therapy

H Yamamoto, M Asoh, H Murakami, N Kamiyama… - Pediatric …, 1998 - Elsevier
Dexamethasone palmitate (liposteroid) was used for the treatment of West syndrome and
compared with adrenocorticotropic hormone (ACTH) therapy. A single intravenous injection …

West syndrome: individualized ACTH therapy

H Heiskala, R Riikonen, P Santavuori, O Simell… - Brain and …, 1996 - Elsevier
Individualized ACTH treatment of the West syndrome (WS) was assessed in a prospective
multicenter study, in which each patient's dosage was increased stepwise according to …

ACTH therapy for Taiwanese children with West syndrome—efficacy and impact on long-term prognosis

HC Lin, C Young, PJ Wang, WT Lee, YZ Shen - Brain and Development, 2006 - Elsevier
To study the efficacy of adrenocorticotrophic hormone (ACTH) in treating Taiwanese
children with West syndrome (WS) and the impact on long-term prognosis, 66 patients with …

Efficacy of long‐term adrenocorticotropic hormone therapy for West syndrome: a retrospective multicenter case series

S Baba, T Okanishi, Y Homma, T Yoshida… - Epilepsia …, 2021 - Wiley Online Library
Objectives Long‐term adrenocorticotropic therapy (LT‐ACTH), which consisted of 2‐4
weeks of daily injections of adrenocorticotropic hormone (ACTH) and subsequent months of …