Advanced maternal age and the impact on maternal and offspring cardiovascular health

CLM Cooke, ST Davidge - American Journal of Physiology …, 2019 - journals.physiology.org
Delaying pregnancy, which is on the rise, may increase the risk of cardiovascular disease in
both women and their children. The physiological mechanisms that lead to these effects are …

Pregnancy and cardiovascular disease

KP Ramlakhan, MR Johnson… - Nature Reviews …, 2020 - nature.com
Abstract Cardiovascular disease complicates 1–4% of pregnancies—with a higher
prevalence when including hypertensive disorders—and is the leading cause of maternal …

Maternal cardiovascular disorders before and during pregnancy and offspring cardiovascular risk across the life course

R Gaillard, VWV Jaddoe - Nature Reviews Cardiology, 2023 - nature.com
Obesity, hypertension, type 2 diabetes mellitus and dyslipidaemia are highly prevalent
among women of reproductive age and contribute to complications in> 30% of pregnancies …

Maternal inflammation, growth retardation, and preterm birth: insights into adult cardiovascular disease

LK Rogers, M Velten - Life sciences, 2011 - Elsevier
The “fetal origin of adult disease Hypothesis” originally described by Barker et al. identified
the relationship between impaired in utero growth and adult cardiovascular disease risk and …

Effect of maternal cardiovascular conditions and risk factors on offspring cardiovascular disease

W Palinski - Circulation, 2014 - Am Heart Assoc
Cardiovascular diseases (CVDs) constitute a particular challenge during pregnancy
because physiological changes and fetal demands create an additional burden and fetal …

Preterm delivery and maternal cardiovascular disease in young and middle-aged adult women

LJ Tanz, JJ Stuart, PL Williams, EB Rimm, SA Missmer… - Circulation, 2017 - Am Heart Assoc
Background: Preterm delivery has been shown to be associated with increased risk of
cardiovascular disease (CVD), but it is unknown whether this risk remains after adjustment …

Pregnancy as an early cardiovascular moment: peripartum cardiovascular health

SS Khan, NA Cameron, KJ Lindley - Circulation research, 2023 - Am Heart Assoc
Pregnancy is commonly referred to as a window into future CVH (cardiovascular health).
During pregnancy, physiological adaptations occur to promote the optimal growth and …

Impact of the vulnerable preterm heart and circulation on adult cardiovascular disease risk

AJ Lewandowski, PT Levy, ML Bates, PJ McNamara… - …, 2020 - Am Heart Assoc
Preterm birth accounts for over 15 million global births per year. Perinatal interventions
introduced since the early 1980s, such as antenatal glucocorticoids, surfactant, and invasive …

Preeclampsia, prematurity and cardiovascular health in adult life

AJ Lewandowski, P Leeson - Early human development, 2014 - Elsevier
Investigations into how perinatal growth and intrauterine environment may 'programme'risk
of later cardiovascular disease have been ongoing for over two decades. One of the more …

Fetal hemodynamic adaptive changes related to intrauterine growth: the Generation R Study

BO Verburg, VWV Jaddoe, JW Wladimiroff, A Hofman… - circulation, 2008 - Am Heart Assoc
Background—It has been suggested that an adverse fetal environment increases
susceptibility to hypertension and cardiovascular disease in adult life. This increased risk …