NF-κB, A potential therapeutic target in cardiovascular diseases
W Cheng, C Cui, G Liu, C Ye, F Shao… - … Drugs and Therapy, 2023 - Springer
Cardiovascular diseases (CVDs) are the leading cause of death globally. Atherosclerosis is
the basis of major CVDs–myocardial ischemia, heart failure, and stroke. Among numerous …
the basis of major CVDs–myocardial ischemia, heart failure, and stroke. Among numerous …
Relevance of new drug discovery to reduce NF-κB activation in cardiovascular disease
R Madonna, R De Caterina - Vascular pharmacology, 2012 - Elsevier
The transcription factor nuclear factor-κB (NF-κB) is a main regulator of the expression of
several genes involved in the activation of inflammation, cell proliferation, cell immunity and …
several genes involved in the activation of inflammation, cell proliferation, cell immunity and …
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB): a new potential therapeutic target in atherosclerosis?
J Dąbek, A Kułach, Z Gąsior - Pharmacological reports, 2010 - Elsevier
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a crucial
transcription factor that participates in a number of physiological and pathological …
transcription factor that participates in a number of physiological and pathological …
Transcription factor NF-κB: an update on intervention strategies
The nuclear factor (NF)-κB family of transcription factors are ubiquitous and pleiotropic
molecules that regulate the expression of more than 150 genes involved in a broad range of …
molecules that regulate the expression of more than 150 genes involved in a broad range of …
Role of nuclear factor κB in cardiovascular health and disease
K Van der Heiden, S Cuhlmann, LA Luong… - Clinical …, 2010 - portlandpress.com
Cardiovascular pathologies are still the primary cause of death worldwide. The molecular
mechanisms behind these pathologies have not been fully elucidated. Unravelling them will …
mechanisms behind these pathologies have not been fully elucidated. Unravelling them will …
NF-κB signaling in inflammation
The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune
functions and serves as a pivotal mediator of inflammatory responses. NF-κB induces the …
functions and serves as a pivotal mediator of inflammatory responses. NF-κB induces the …
Nuclear factor-κB: its role in health and disease
A Kumar, Y Takada, AM Boriek… - Journal of molecular …, 2004 - Springer
Nuclear factor-κB (NF-κB) is a major transcription factor that plays an essential role in
several aspects of human health including the development of innate and adaptive …
several aspects of human health including the development of innate and adaptive …
Roles of NF-κB in cancer and inflammatory diseases and their therapeutic approaches
MH Park, JT Hong - Cells, 2016 - mdpi.com
Nuclear factor-κB (NF-κB) is a transcription factor that plays a crucial role in various
biological processes, including immune response, inflammation, cell growth and survival …
biological processes, including immune response, inflammation, cell growth and survival …
Cardiac role of the transcription factor NF-κB
SH Gutierrez, MR Kuri… - … Disorders-Drug Targets …, 2008 - ingentaconnect.com
The signaling pathways that control the life-death switch of a cell are of primary interest in
modern biology. In this respect, NF-?? B has emerged as a decisive transcription factor in …
modern biology. In this respect, NF-?? B has emerged as a decisive transcription factor in …
The nuclear factor–kappa B pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease
Nuclear factor kappa B (NFκB) is a transcription factor belonging to 'Rel'family that
represents a crucial intracellular signal transduction system involved in several inflammatory …
represents a crucial intracellular signal transduction system involved in several inflammatory …
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