Objective: This study is to identify and investigate the proteins interacting with pORF5
implicated in the pathogenesis of C. trachomatis. Methods: The isobaric tags for relative and …

Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …

Chlamydia trachomatis is an important human pathogen responsible for a variety of
important diseases. pORF5, a plasmid protein in C. trachomatis, has been reported to …

Infection with Chlamydia trachomatis induces inflammatory pathologies in the urogenital
tract that can lead to infertility and ectopic pregnancy. Pathogenesis of infection has been …

Chlamydia trachomatis, an obligate intracellular pathogen, has various effective strategies to
regulate host cell death signalling pathways that ensure completion of their growth cycle …

As an obligate intracellular pathogen, Chlamydia trachomatis assumes various strategies to
inhibit host cells apoptosis, thereby providing a suitable intracellular environment to ensure …

The pathogenesis of Chlamydia-induced inflammation is poorly understood. pORF5 is the
only secreted protein encoded by Chlamydial plasmid. This study aims to investigate the …

Aim Chlamydia trachomatis has evolved various strategies to alleviate oxidative stress of
host cells to maintain their intracellular survival. However, the exact mechanism of anti …

Persistent infection of Chlamydia trachomatis is thought to be responsible for the debilitating
sequelae of blinding trachoma and infertility. Inhibition of host cell apoptosis is a persistent …

Chlamydia trachomatis has evolved strategies to prevent host cell apoptosis to evade the
host immune defense. However, the precise mechanisms of antiapoptotic activity of C …