Listeria monocytogenes, a facultative intracellular bacterium, can induce a potent antitumor
immune response if engineered to express a model tumor antigen also expressed by the …

The bacterium L. monocytogenes is a proposed vaccine carrier based upon the observation
that this pathogen replicates within the intracytoplasmic environment facilitating delivery of …

Listeria monocytogenes is a facultative intracellular gram‐positive bacterium that naturally
infects professional antigen presenting cells (APC) to target antigens to both class I and …

One of the main objectives of developing new anti-cancer vaccine strategies is to effectively
induce CD8+ T cell-mediated anti-tumor immunity. Live recombinant vectors, notably Listeria …

As a facultative intracellular bacterium, Listeria monocytogenes has adapted to live within
the cytosol of the host cell. It is actively taken up by antigen-presenting cells through …

The facultative intracellular bacterium Listeria monocytogenes is being developed as a
cancer vaccine platform because of its ability to induce potent innate and adaptive immunity …

Improved immunization and ex vivo T-cell culture strategies can generate larger numbers
and more potent tumor-specific effector cells than previously possible. Nonetheless, the …

Abstract Purpose of Review Immunotherapy has emerged as a promising cancer treatment;
however, success in only select clinical indications underscores the need for novel …

Cancer receives enduring international attention due to its extremely high morbidity and
mortality. Immunotherapy, which is generally expected to overcome the limits of traditional …

Listeria monocytogenes is an intracellular organism that has the unusual ability to live in the
cytoplasm of the cell. It is thus a good vector for targeting protein antigens to the cellular arm …