Nontoxic Cobalt (III) Schiff Base Complexes with Broad‐Spectrum Antifungal Activity

A Frei, AP King, GJ Lowe, AK Cain… - … A European Journal, 2021 - Wiley Online Library
Resistance to currently available antifungal drugs has quietly been on the rise but
overshadowed by the alarming spread of antibacterial resistance. There is a striking lack of …

[引用][C] Metal complexes as drugs and chemotherapeutic agents

N Farrell - 2003 - Elsevier

[PDF][PDF] Synthesis, structure, and pharmacological evaluation of Co (III) complex containing tridentate Schiff base ligand

KS Jone, R Velmurugan, R Karvembu… - Координационная …, 2015 - researchgate.net
Schiff bases and their complexes have a variety of applications including biological, clinical
and analyti cal, and have been extensively studied over the past few decades [1–3]. Schiff …

Cobalt derivatives as promising therapeutic agents

MC Heffern, N Yamamoto, RJ Holbrook… - Current opinion in …, 2013 - Elsevier
Inorganic complexes are versatile platforms for the development of potent and selective
pharmaceutical agents. Cobalt possesses a diverse array of properties that can be …

Physical properties, ligand substitution reactions, and biological activity of Co (iii)-Schiff base complexes

AP King, HA Gellineau, SN MacMillan, JJ Wilson - Dalton Transactions, 2019 - pubs.rsc.org
Four cobalt (III) complexes of the general formula [Co (Schiff base)(L) 2]+, where L is
ammonia (NH3) or 3-fluorobenzylamine (3F-BnNH2), were synthesized. The complexes …

Axial Ligand Exchange of N-heterocyclic Cobalt(III) Schiff Base Complexes: Molecular Structure and NMR Solution Dynamics

LM Manus, RJ Holbrook, TA Atesin… - Inorganic …, 2013 - ACS Publications
The kinetic and thermodynamic ligand exchange dynamics are important considerations in
the rational design of metal-based therapeutics and therefore, require detailed investigation …

Development of new cobalt, copper, and zinc complexes of Schiff-base ligands as prospective chemotherapeutic agents

VS Narayanan, A Rajendran, S Mudradi, S Dhawa… - Polyhedron, 2023 - Elsevier
Fluorobenzaldehyde was converted into new, bidentate Schiff-base ligands with nitrogen
and sulphur donor sites in two steps. The first step proceeds via Knoevenagel condensation; …

New trends for metal complexes with anticancer activity

PCA Bruijnincx, PJ Sadler - Current opinion in chemical biology, 2008 - Elsevier
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …

Metal complexes for therapeutic applications

J Karges, RW Stokes, SM Cohen - Trends in chemistry, 2021 - cell.com
Metal complexes have been widely used for applications in the chemical and physical
sciences due to their unique electronic and stereochemical properties. For decades the use …

Metals and metal derivatives in medicine

G Colotti, A Ilari, A Boffi, V Morea - Mini reviews in medicinal …, 2013 - ingentaconnect.com
Several chemical elements are required by living organisms in addition to the four elements
carbon, hydrogen, nitrogen and oxygen usually present in common organic molecules …