Epigenetic modifications, such as DNA methylation, is widely studied in cancer. DNA
methylation patterns have been shown to distinguish between benign and malignant tumors …

Background: Prostate cancer (PCa) harbors a myriad of genomic and epigenetic defects.
Cytosine methylation of CpG-rich promoter DNA is an important mechanism of epigenetic …

Introduction 3. DNA Hypermethylation, Heterochromatin, and Epigenetic Gene Silencing 4.
DNA Hypomethylation, Demethylation, and Loss of Imprinting 5. DNA Methyltransferases …

Epigenetic alterations contribute significantly to the development and progression of
prostate cancer, the most prevalent malignant tumor in males of Western industrialized …

The prostate gland is the most common site of cancer and the second leading cause of
cancer death in American men. Recent emerging molecular biological technologies help us …

Prostate cancer is the most common malignancy and the second leading cause of cancer
death among men in the United States. There are three well-established risk factors for …

Background Epigenetic silencing mediated by CpG island methylation is a common feature
of many cancers. Characterizing aberrant DNA methylation changes associated with …

Epigenetic silencing mediated by CpG methylation is a common feature of many cancers.
Characterizing aberrant DNA methylation changes associated with tumor progression may …

CpG island hypermethylation may be one of the earliest somatic genome alterations to occur
during the development of multiple cancers. Recently, aberrant methylation patterns for …

Prostate cancer is one of the most common malignancies in men worldwide. Current clinical
screening ensures that most prostate cancers are diagnosed while still organ confined, but …