Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS

R Zivadinov, K Marr, G Cutter, M Ramanathan… - Neurology, 2011 - AAN Enterprises
Background: Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in
patients with multiple sclerosis (MS). A subject is considered CCSVI positive if≥ 2 venous …

No evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset

C Baracchini, P Perini, M Calabrese… - Annals of …, 2011 - Wiley Online Library
Objective An impaired cerebrospinal venous drainage, defined as chronic cerebrospinal
venous insufficiency (CCSVI), has been recently hypothesized to be the possible cause of …

Chronic cerebrospinal venous insufficiency and multiple sclerosis: a comprehensive meta-analysis of case–control studies

G Tsivgoulis, TN Sergentanis, A Chan… - Therapeutic …, 2014 - journals.sagepub.com
Objectives: Chronic cerebrospinal venous insufficiency (CCSVI) has recently been
implicated in the pathogenesis of multiple sclerosis (MS). This comprehensive meta-analysis …

Occurrence of CCSVI in patients with MS and its relationship with iron metabolism and varicose veins

PJ Van den Berg, GB Van den Berg… - European journal of …, 2013 - Wiley Online Library
Background and purpose A new treatable venous disorder, chronic cerebrospinal venous
insufficiency (CCSVI), has been proposed in patients with multiple sclerosis (MS). Its …

Chronic cerebrospinal venous insufficiency and multiple sclerosis

O Khan, M Filippi, MS Freedman, F Barkhof… - Annals of …, 2010 - Wiley Online Library
A chronic state of impaired venous drainage from the central nervous system, termed
chronic cerebrospinal venous insufficiency (CCSVI), is claimed to be a pathologic …

The hypothesis of pathophysiological correlation between chronic cerebrospinal venous insufficiency and multiple sclerosis: rationale of treatment

M Lugli, M Morelli, S Guerzoni, O Maleti - Phlebology, 2012 - journals.sagepub.com
Background: The possible role of the venous system in the pathogenesis of chronic
neurodegenerative diseases has been hypothesized for decades. Quite recently, the …

Chronic cerebrospinal venous insufficiency: case–control neurosonography results

AD Barreto, SA Brod, TT Bui, JR Jemelka… - Annals of …, 2013 - Wiley Online Library
Objective Chronic cerebrospinal venous insufficiency (CCSVI) has been implicated in the
pathophysiology of multiple sclerosis (MS). We sought to determine whether …

Chronic cerebrospinal venous insufficiency: report of transcranial magnetic stimulation follow-up study in a patient with multiple sclerosis

R Plasmati, F Pastorelli, N Fini, F Salvi… - International …, 2010 - search.proquest.com
The pyramidal pathway is frequently affected early on in multiple sclerosis (MS) and
impaired motor performance is a major cause of disability. Pyramidal tract function can be …

Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity

D Centonze, R Floris, M Stefanini, S Rossi… - Annals of …, 2011 - Wiley Online Library
Objective: It is still unclear whether chronic cerebrospinal venous insufficiency (CCSVI) is
associated with multiple sclerosis (MS), because substantial methodological differences …

Chronic cerebrospinal venous insufficiency and multiple sclerosis: history and background

MD Dake - Techniques in vascular and interventional radiology, 2012 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system
(CNS) most commonly characterized by focal areas of myelin destruction, inflammation and …