The cerebrocortical microcirculatory effect of nitric oxide synthase blockade is dependent upon baseline red blood cell flow in the rat

Z Lacza, B Erdős, C Görlach, M Wahl, P Sándor… - Neuroscience …, 2000 - Elsevier
The effects of nitric oxide synthase (NOS) blockade on the cerebrocortical microcirculation
were investigated under physiological conditions in anesthetized ventilated rats using laser …

Nitric oxide from neuronal NOS plays critical role in cerebral capillary flow response to hypoxia

AG Hudetz, H Shen… - American Journal of …, 1998 - journals.physiology.org
We investigated, using a direct, intravital microscopic technique, whether nitric oxide (NO)
from neuronal nitric oxide synthase (nNOS) plays a role in the cerebral capillary flow …

NOS activity in brain and endothelium: relation to hypercapnic rise of cerebral blood flow in rats

M Fabricius, I Rubin, M Bundgaard… - American Journal of …, 1996 - journals.physiology.org
We examined whether attenuation of the hypercapnic increase of cerebral blood flow (CBF)
associated with nitric oxide synthase (NOS) inhibition is related to local neuronal or aortic …

Role of nitric oxide in the coupling of cerebral blood flow to neuronal activation in rats

U Dirnagl, U Lindauer, A Villringer - Neuroscience letters, 1993 - Elsevier
We tested the hypothesis that nitric oxide (NO) is a mediator in the coupling of cerebral
blood flow to neuronal activation. The production of NO was blocked in anesthetized rats …

Regulation of the cerebral microcirculation during neural activity: is nitric oxide the missing link?

C Iadecola - Trends in neurosciences, 1993 - Elsevier
Although the mechanisms regulating the cerebral microcirculation during neural activity
have been the subject of inquiry for a century or more, the mediators responsible for the …

Nitric oxide (NO) is involved in increased cerebral cortical blood flow following stimulation of the nucleus basalis of Meynert in anesthetized rats

T Adachi, O Inanami, A Sato - Neuroscience letters, 1992 - Elsevier
The effects of iv administration of a nitric oxide (NO) synthase inhibitor, lN G-nitroarginine (l-
NOArg), on the increase in cerebral cortical blood flow (cortical BF), following either …

Neuronal NO promotes cerebral cortical hyperemia during cortical spreading depression in rabbits

DM Colonna, W Meng, DD Deal… - American Journal of …, 1997 - journals.physiology.org
Temporary elevations in cortical cerebral blood flow (CBF) accompany cortical spreading
depression (CSD) in anesthetized animals. We tested the hypothesis that nitric oxide (NO) is …

Role of nitric oxide in regulation of cerebral microvascular tone and autoregulation of cerebral blood flow in cats

M Kobari, Y Fukuuchi, M Tomita, N Tanahashi… - Brain research, 1994 - Elsevier
The role of nitric oxide in the regulation of cerebrocortical microvascular tone and
autoregulation of cerebral blood flow (CBF) was examined in 24 anesthetized cats. The local …

Nitric oxide synthase does not contribute to cerebral autoregulatory phenomenon in anesthetized dogs

S Saito, DA Wilson, DF Hanley, RJ Traystman - Journal of the autonomic …, 1994 - Elsevier
Nitric oxide (NO) is a potent vasodilator produced by nitric oxide synthase (NOS). We tested
the following hypotheses:(1) cerebral blood flow (CBF) is NO dependent,(2) NO contributes …

Inhibition of nitric oxide synthesis impairs autoregulation of local cerebral blood flow in the rat

K Tanaka, Y Fukuuchi, S Gomi, B Mihara, T Shirai… - …, 1993 - journals.lww.com
THE effect of intravenous administration of N G-monomethyl-L-arginine (L-NMMA, 30 mg kg-
1), a specific inhibitor of nitric oxide (NO) synthesis, on the autoregulation of local cerebral …