Abstract Purpose Direct oral anticoagulants (DOACs) are recommended in preference to
vitamin K antagonists (VKAs) for stroke prevention in patients with atrial fibrillation (AF) …

Abstract Background Direct oral anticoagulants (DOACs) have become favorable choices for
anticoagulation due to their fixed-dose schedule, limited need for monitoring, and non …

Background Because studies of direct oral anticoagulants in patients with venous
thromboembolism and non-valvular atrial fibrillation have had minimal representation of …

Direct acting non-Vitamin K antagonist oral anticoagulants (NOAC) are characterized by a
fixed dosing regimen. Despite the potential for relative underdosing due to large distribution …

The health implications of obesity are myriad and multifaceted. Physiologic changes
associated with obesity can affect the absorption, distribution, metabolism, and excretion of …

Background Randomized clinical trials comparing the efficacy and safety of direct oral
anticoagulants (DOAC) with vitamin K antagonist (VKA) or low molecular weight heparin …

Obesity is a significant cause of morbidity and mortality, and it is becoming increasingly
prevalent worldwide. Altered pharmacodynamics and pharmacokinetics of drugs in obese …

Background: Direct oral anticoagulants (DOACs) have been increasingly preferred over
warfarin; however, The International Society of Thrombosis and Hemostasis recommended …

Background There is scarce evidence on the effectiveness and safety of recommended-
dose direct acting oral anticoagulants (DOACs) in obese patients with venous …

Introduction: The landscape of therapeutic anticoagulation has changed dramatically over
the past decade, with availability of direct oral anticoagulants (DOACs), which inhibit factor …