Genetic engineering of a thermophilic acetogen, Moorella thermoacetica Y72, to enable acetoin production

J Kato, T Fujii, S Kato, K Wada, M Watanabe… - … in Bioengineering and …, 2024 - frontiersin.org
Acetogens are among the key microorganisms involved in the bioproduction of commodity
chemicals from diverse carbon resources, such as biomass and waste gas. Thermophilic …

[HTML][HTML] Thermophilic Moorella thermoacetica as a platform microorganism for C1 gas utilization: physiology, engineering, and applications

D Jia, W Deng, P Hu, W Jiang, Y Gu - Bioresources and Bioprocessing, 2023 - Springer
In the context of the rapid development of low-carbon economy, there has been increasing
interest in utilizing naturally abundant and cost-effective one-carbon (C1) substrates for …

[HTML][HTML] Metabolic engineering of Moorella thermoacetica for thermophilic bioconversion of gaseous substrates to a volatile chemical

J Kato, K Takemura, S Kato, T Fujii, K Wada, Y Iwasaki… - Amb Express, 2021 - Springer
Gas fermentation is one of the promising bioprocesses to convert CO2 or syngas to
important chemicals. Thermophilic gas fermentation of volatile chemicals has the potential …

Homolactic acid fermentation by the genetically engineered thermophilic homoacetogen Moorella thermoacetica ATCC 39073

Y Iwasaki, A Kita, K Yoshida, T Tajima… - Applied and …, 2017 - Am Soc Microbiol
For the efficient production of target metabolites from carbohydrates, syngas, or H2-CO2 by
genetically engineered Moorella thermoacetica, the control of acetate production (a main …

Latest advances of microbial production of platform chemical acetoin

X LIU, J FU, G HUO, B ZHANG… - China …, 2015 - manu60.magtech.com.cn
Abstract Acetoin (3-hydroxy-2-butanone), widely used mainly in foods as an additive to
enhance the flavor and in chemical synthesis as a platform chemical, has broad industrial …

[HTML][HTML] Developing a genetic engineering method for Acetobacterium wieringae to expand one-carbon valorization pathways

JPC Moreira, JT Heap, JI Alves… - Biotechnology for Biofuels …, 2023 - Springer
Background Developing new bioprocesses to produce chemicals and fuels with reduced
production costs will greatly facilitate the replacement of fossil-based raw materials. In most …

[HTML][HTML] Enabling Ethanologenesis in Moorella thermoacetica through Construction of a Replicating Shuttle Vector

B Bourgade, J Millard, CM Humphreys, NP Minton… - Fermentation, 2022 - mdpi.com
Replicating plasmid shuttle vectors are key tools for efficient genetic and metabolic
engineering applications, allowing the development of sustainable bioprocesses using non …

Autotrophic growth and ethanol production enabled by diverting acetate flux in the metabolically engineered Moorella thermoacetica

K Takemura, J Kato, S Kato, T Fujii, K Wada… - Journal of bioscience …, 2021 - Elsevier
Gas fermentation is a promising biological process for the conversion of CO 2 or syngas into
valuable chemicals. Homoacetogens are microorganisms growing autotrophically using CO …

Engineered acetogenic bacteria as microbial cell factory for diversified biochemicals

JZ Zhang, YZ Li, ZN Xi, HP Gao, Q Zhang… - … in Bioengineering and …, 2024 - frontiersin.org
Acetogenic bacteria (acetogens) are a class of microorganisms with conserved Wood-
Ljungdahl pathway that can utilize CO and CO2/H2 as carbon source for autotrophic growth …

Strategies for enhancing fermentative production of acetoin: a review

Z Xiao, JR Lu - Biotechnology advances, 2014 - Elsevier
Acetoin is a volatile compound widely used in foods, cigarettes, cosmetics, detergents,
chemical synthesis, plant growth promoters and biological pest controls. It works largely as …