Actions of thyroid hormones in bone

GR Williams - Endokrynologia Polska, 2009 - journals.viamedica.pl
Thyroid hormones are required for skeletal development and establishment of peak bone
mass. Hypothyroidism in children results in growth retardation with delayed skeletal …

Thyroid and bone

AI Gogakos, JHD Bassett, GR Williams - Archives of biochemistry and …, 2010 - Elsevier
The hypothalamic–pituitary–thyroid axis plays a key role in skeletal development,
acquisition of peak bone mass and regulation of adult bone turnover. Euthyroid status is …

Thyroid hormone actions in cartilage and bone

GR Williams - European thyroid journal, 2013 - etj.bioscientifica.com
Thyroid hormones exert widespread and complex actions in almost all tissues during
development, throughout childhood and in adults. The skeleton is an important T3-target …

Effects of thyroid status on bone metabolism: a primary role for thyroid stimulating hormone or thyroid hormone?

TM Galliford, E Murphy, AJ Williams… - Minerva …, 2005 - europepmc.org
Thyroid hormones are essential for normal skeletal growth and the maintenance of bone
mass in adulthood, although their mechanism of action in bone is poorly understood …

The molecular actions of thyroid hormone in bone

JHD Bassett, GR Williams - Trends in Endocrinology & Metabolism, 2003 - cell.com
Thyroid hormone (T 3) is essential for the normal development of endochondral and
intramembranous bone and plays an important role in the linear growth and maintenance of …

A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone

PJ O'Shea, CB Harvey, H Suzuki… - Molecular …, 2003 - academic.oup.com
Thyroid hormone (T3) regulates bone turnover and mineralization in adults and is essential
for skeletal development during childhood. Hyperthyroidism is an established risk factor for …

Mechanisms of action of thyroid hormones in the skeleton

A Wojcicka, JHD Bassett, GR Williams - Biochimica et Biophysica Acta (BBA …, 2013 - Elsevier
BACKGROUND: Thyroid hormones regulate skeletal development, acquisition of peak bone
mass and adult bone maintenance. Abnormal thyroid status during childhood disrupts bone …

Thyroid diseases and bone health

GR Williams, JHD Bassett - Journal of endocrinological investigation, 2018 - Springer
Thyroid hormones are essential for skeletal development and are important regulators of
bone maintenance in adults. Childhood hypothyroidism causes delayed skeletal …

Thyroid-stimulating hormone, thyroid hormones, and bone loss

M Zaidi, TF Davies, A Zallone, HC Blair, J Iqbal… - Current osteoporosis …, 2009 - Springer
It has become accepted by virtue of rich anecdotal experience and clinical research that
thyrotoxicosis is associated with high-turnover osteoporosis. The bone loss, primarily due to …

Thyroid status during skeletal development determines adult bone structure and mineralization

JHD Bassett, K Nordstrom, A Boyde… - Molecular …, 2007 - academic.oup.com
Childhood hypothyroidism delays ossification and bone mineralization, whereas adult
thyrotoxicosis causes osteoporosis. To determine how effects of thyroid hormone (T3) during …