New Perspectives on Cholesterol and Lipoprotein Metabolism

B De Geest, M Mishra - International Journal of Molecular Sciences, 2023 - mdpi.com
In animals, cholesterol is an essential component of every cellular membrane and is
required for cell membrane integrity. Cholesterol is insoluble in water but is solubilized by …

Smith-Lemli-Opitz syndrome: A pathophysiological manifestation of the Bloch hypothesis

A Chattopadhyay, A Sharma - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
The biosynthesis of cholesterol, an essential component of higher eukaryotic membranes,
was worked out by Konrad Bloch (and Feodor Lynen) in the 1960s and they received the …

Physiological role of cholesterol in human body

MS Sekhar, S Marupuru, BS Reddy, SJ Kurian… - Dietary sugar, salt and …, 2020 - Elsevier
Cholesterol is a biomolecule present in almost all cells of the human body. Cholesterol has
a bidirectional (both good and bad) role in the body. The chapter focuses on chemistry …

[HTML][HTML] Biochemistry, cholesterol

M Craig, SNS Yarrarapu, M Dimri - 2018 - europepmc.org
Cholesterol is a structural component of cell membranes and serves as a building block for
synthesizing various steroid hormones, vitamin D, and bile acids. Besides their structural …

Smith–Lemli–Opitz syndrome and other disorders of cholesterol biosynthesis: An introduction

MJM Nowaczyk, C Cunniff - … Journal of Medical Genetics Part C …, 2012 - Wiley Online Library
This issue of Seminars of Medical Genetics features a series of articles on Smith–Lemli–
Opitz syndrome and other disorders of endogenous cholesterol synthesis. Clinically, many …

Significance of lipid and lipoprotein in organism

MZ Jovandaric, SJ Milenkovic - … , Triglycerides and Cholesterol, 2020 - books.google.com
Lipids are important energy and building compounds. Their decomposition provides a
significant amount of energy required for various life processes. It can thus be deposited in …

[PDF][PDF] The major pathways of lipids (triglyceride and cholesterol) and lipoprotein metabolism

KJ Salih - Zanco Journal of Pure and Applied Sciences, 2021 - iasj.net
Lipids are considered as organic substances that are relatively insoluble in water while
soluble in organic solvents such as alcohol and ether. Unlike carbohydrates, proteins and …

[PDF][PDF] Mechanisms for controlling the synthesis of Lipids–Review

AI Airaodion, U Ogbuagu, EO Ogbuagu, AP Oloruntoba… - Int. J. Res, 2019 - academia.edu
Lipids are synthesized, transported, and recognized by the concerted actions of numerous
enzymes, binding proteins, and receptors. A comprehensive analysis of lipid …

The role of cholesterol in embryogenesis and the Smith-Lemli-Opitzov syndrom

K Kolejáková, R Petrovic, P Turcáni… - Ceskoslovenská …, 2010 - europepmc.org
The role of cholesterol in cell biology has been known for years. The sight of cholesteol
biological function has changed after the discovery that the genetic disorder Smith-Lemli …

Facts about fats: new insights into the role of lipids in metabolism, disease and therapy

M Segatto, V Pallottini - International journal of molecular sciences, 2020 - mdpi.com
Although initially regarded as a passive system to store energy, lipids are now considered to
play crucial, structural and functional roles in almost all the biological processes involved in …