Early diagnosis of sepsis: is an integrated omics approach the way forward?

RJ Langley, HR Wong - Molecular diagnosis & therapy, 2017 - Springer
Sepsis remains one of the leading causes of death in the USA and it is expected to get
worse as the population ages. Moreover, the standard of care, which recommends …

Sepsis diagnostics in the era of “omics” technologies

M Průcha, R Zazula, S Russwurm - Prague Medical Report, 2018 - karolinum.cz
Sepsis is a multifactorial clinical syndrome with an extremely dynamic clinical course and
with high diverse clinical phenotype. Early diagnosis is crucial for the final clinical outcome …

Basal procalcitonin, C-reactive protein, interleukin-6, and presepsin for prediction of mortality in critically ill septic patients: a systematic review and meta-analysis

D Molano-Franco, I Arevalo-Rodriguez, A Muriel… - Diagnostic and …, 2023 - Springer
Background Numerous biomarkers have been proposed for diagnosis, therapeutic, and
prognosis in sepsis. Previous evaluations of the value of biomarkers for predicting mortality …

[HTML][HTML] New sepsis biomarkers

D Limongi, C D'Agostini, M Ciotti - Asian Pacific Journal of Tropical …, 2016 - Elsevier
Sepsis remains a leading cause of death in the intensive care units and in all age groups
worldwide. Early recognition and diagnosis are key to achieving improved outcomes …

Biomarkers: diagnosis and risk assessment in sepsis

CE Ventetuolo, MM Levy - Clinics in chest medicine, 2008 - Elsevier
Prompt diagnosis, intervention, and risk assessment are critical in caring for patients who
have sepsis but remain difficult with currently available methods. Biomarkers may become …

Future perspectives in the diagnosis and treatment of sepsis and septic shock

I Karampela, PC Fragkou - Medicina, 2022 - mdpi.com
Sepsis, defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection, represents the primary cause of death due to infection [1]. Unless …

Diagnostic methods in sepsis: the need of speed

FR Coelho, JO Martins - Revista da Associação Médica Brasileira (English …, 2012 - Elsevier
Objective Sepsis is a common condition encountered in hospital environments. There is no
effective treatment for sepsis, and it remains an important cause of death at intensive care …

Toward an operative diagnosis in sepsis: a latent class approach

GD De La Rosa, ML Valencia, CM Arango… - BMC Infectious …, 2008 - Springer
Background Recent data have suggested that 18 million of new sepsis cases occur each
year worldwide, with a mortality rate of almost 30%. There is not consensus on the clinical …

[PDF][PDF] Clinical biomarkers in sepsis

R Anderson, R Schmidt - Front Biosci (Elite Ed), 2010 - article.imrpress.com
[Frontiers in Bioscience E2, 504-520, January 1, 2010] 504 Clinical biomarkers in sepsis Rudolf
Anderson, Rene Schmidt Departmen Page 1 [Frontiers in Bioscience E2, 504-520, January 1 …

A current appraisal of evidence for the approach to sepsis and septic shock

J Varon, RM Baron - Therapeutic Advances in Infectious …, 2019 - journals.sagepub.com
Sepsis is a life-threatening syndrome of a dysregulated host response to infection. Despite
advances in diagnosis and treatment, sepsis remains a significant cause of morbidity and …