Competence for genetic transformation in Streptococcus pneumoniae and Streptococcus
gordonii involves the ComAB secretion apparatus, which is thought to export the …

Recently, we described the function of an uncharacterized two‐gene regulatory system
consisting of a LytTR family transcription regulator and a putative membrane protein, which …

Streptococcus mutans expresses comX (also known as sigX), which encodes a sigma factor
that is required for development of genetic competence, in response to the peptide signals …

Natural genetic transformation is common among many species of the genus Streptococcus,
but it has never, or rarely, been reported for the Streptococcus pyogenes and S. bovis …

The com operon of naturally transformable streptococcal species contains three genes,
comC, comD, and comE, involved in the regulation of competence. The comC gene encodes …

In Streptococcus pneumoniae, competence and bacteriocin genes are controlled by two two-
component systems, ComED and BlpRH, respectively. In Streptococcus mutans, both …

The human pathogens Streptococcus pneumoniae and Streptococcus mutans have both
evolved complex quorum sensing (QS) systems that regulate the production of bacteriocins …

Bacteria use quorum‐sensing signals or autoinducers to communicate. The signals in Gram‐
positive bacteria are often peptides activated by proteolytic removal of an N‐terminal leader …

Gram-positive bacteria secrete a variety of peptides that are often subjected to
posttranslational modifications and that are either antimicrobials or pheromones involved in …

In many streptococci, competence for natural DNA transformation is regulated by the Rgg‐
type regulator ComR and the pheromone ComS, which is sensed intracellularly. We …