Inflammation has been implicated as a secondary injury mechanism following ischemia and
stroke. A variety of experimental models, including thromboembolic stroke, focal and global …

BACKGROUND: A growing number of recent investigations have established a critical role
for leukocytes in propagating tissue damage after ischemia and reperfusion in stroke …

Inflammation is a defense reaction against diverse insults that serves to remove noxious
agents and to limit their detrimental effects. There is increasing evidence that post-ischemic …

Review on the time-dependent recruitment of inflammatory cells and unanswered questions
regarding inflammatory cells in the pathophysiology of ischemic stroke. Inflammation plays …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

Ischemic stroke is the most frequent cause of persistent neurologic disability in modern
Western societies. Albeit it is still not clear whether inflammation is merely an …

Reperfusion of ischemic brain can reduce injury and improve outcome, but secondary injury
due to inflammatory mechanisms limits the efficacy and time window of such treatments for …

A growing body of evidence, primarily from animal models of cerebral ischemia and
preliminary human studies, indicates that inflammatory mechanisms contribute to secondary …

Contrary to previous dogmas, it is now well established that brain cells can produce
cytokines and chemokines, and can express adhesion molecules that enable an in situ …

The immune response after stroke is known to play a major role in ischemic brain
pathobiology. The inflammatory signals released by immune mediators activated by brain …