Apolipoprotein (apo) B, the major protein component of the atherogenic low-density
lipoprotein (LDL), has a pentapartite structure, NH2-βα1-β1-α2-β2-α3-COOH, the β domains …

The microsomal triglyceride transfer protein (MTP) is required for assembly and secretion of
the lipoproteins containing apolipoprotein B (apoB): very low density lipoproteins and …

We have explored the minimum sequence requirement for the initiation of apolipoprotein B
(apoB)-mediated triglyceride-rich lipoprotein assembly. A series of apoB COOH-terminal …

We previously demonstrated that the N-terminal 1000 amino acid residues of human
apolipoprotein (apo) B (designated apoB: 1000) are competent to fold into a three-sided …

The initial assembly of apolipoprotein B100 (apoB) into lipoprotein particles occurs
cotranslationally. To examine steps required to initiate this process, the intracellular folding …

The process of assembly of apolipoprotein (apo) B-containing lipoprotein particles occurs co-
translationally after disulfide-dependent folding of the N-terminal domain of apoB but the …

The microsomal triglyceride transfer protein (MTP) is required for the assembly and
secretion of apoB-containing lipoproteins. To investigate the role of MTP in lipoprotein …

Several studies have demonstrated protein-protein interactions between microsomal
triglyceride transfer protein (MTP) and apolipoprotein B (apoB). However, the binding sites …

Apolipoprotein B (apoB) and microsomal triglyceride transfer protein (MTP) are essential for
the efficient assembly and secretion of triglyceride-rich lipoproteins. We have presented …

The microsomal triglyceride transfer protein (MTP) is necessary for the proper assembly of
the apolipoprotein B containing lipoproteins, very low density lipoprotein and chylomicrons …