Advances in urinary proteome analysis and biomarker discovery

D Fliser, J Novak, V Thongboonkerd… - Journal of the …, 2007 - journals.lww.com
Noninvasive diagnosis of kidney diseases and assessment of the prognosis are still
challenges in clinical nephrology. Definition of biomarkers on the basis of proteome …

Human urine proteomics: analytical techniques and clinical applications in renal diseases

S Kalantari, A Jafari, R Moradpoor… - … journal of proteomics, 2015 - Wiley Online Library
Urine has been in the center of attention among scientists of clinical proteomics in the past
decade, because it is valuable source of proteins and peptides with a relative stable …

Pro: urine proteomics as a liquid kidney biopsy: no more kidney punctures!

H Mischak - Nephrology Dialysis Transplantation, 2015 - academic.oup.com
In this article, the benefits of urinary proteomics in comparison with kidney biopsy are
discussed. The majority of urinary proteins are generated by the kidney, hence the urinary …

Renal and urinary proteomics: current applications and challenges

V Thongboonkerd, P Malasit - Proteomics, 2005 - Wiley Online Library
During the past few years, proteomics has been extensively applied to various fields of
medicine including nephrology. Current applications of renal and urinary proteomics are to …

Proteomics in nephrology: current status and future directions

V Thongboonkerd - American journal of nephrology, 2004 - karger.com
Proteomics is one among various 'OMICS'fields that have been growing rapidly in the
postgenomic era. During the past few years, proteomics has been extensively applied to …

Sources of urinary proteins and their analysis by urinary proteomics for the detection of biomarkers of disease

BA Julian, H Suzuki, Y Suzuki, Y Tomino… - PROTEOMICS …, 2009 - Wiley Online Library
Renal disorders account for a substantial fraction of the budget for health care in many
countries. Proteinuria is a frequent manifestation in afflicted patients, but the origin of the …

Urinary proteomics: towards biomarker discovery, diagnostics and prognostics

V Thongboonkerd - Molecular bioSystems, 2008 - pubs.rsc.org
During recent years, the proteomics field has moved onward to clinical applications,
particularly for biomarker discovery, diagnostics and prognostics of human diseases. The …

Urinary proteomics

JM González-Buitrago, L Ferreira, I Lorenzo - Clinica Chimica Acta, 2007 - Elsevier
Protein measurement in urine has been used for many years for the diagnosis and
monitoring of renal disease. The pattern of urinary protein excretion can be used to identify …

Practical points in urinary proteomics

V Thongboonkerd - Journal of proteome research, 2007 - ACS Publications
During the proteomic era, one of the most rapidly growing areas in biomedical research is
biomarker discovery, particularly using proteomic technologies. Urinary proteomics has …

Proteomic biomarkers in kidney disease: issues in development and implementation

H Mischak, C Delles, A Vlahou… - Nature Reviews …, 2015 - nature.com
Proteomic biomarkers offer the hope of improving the management of patients with kidney
diseases by enabling more accurate and earlier detection of renal pathology than is …