Antigen recognition: Current opinion in structural biology 1991, 1: 53–59
C Chothia - Current Opinion in Structural Biology, 1991 - Elsevier
Considerable progress has been made in understanding the relationship between the
sequence and structure of the recognition sites in antibodies and in the MHC proteins …
sequence and structure of the recognition sites in antibodies and in the MHC proteins …
Engineering protein for X‐ray crystallography: The murine major histocompatibility complex class II molecule I‐Ad
CA Scott, K Christoper Garcia, EA Stura… - Protein …, 1998 - Wiley Online Library
Abstract Class II Major Histocompatibility (MHC) molecules are cell surface heterodimeric
glycoproteins that play a central role in the immune response by presenting peptide …
glycoproteins that play a central role in the immune response by presenting peptide …
[HTML][HTML] The crystal structure of H-2Db complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate
A Glithero, J Tormo, K Doering, M Kojima… - Journal of biological …, 2006 - ASBMB
In the absence of bound peptide ligands, major histocompatibility complex (MHC) class I
molecules are unstable. In an attempt to determine the minimum requirement for peptide …
molecules are unstable. In an attempt to determine the minimum requirement for peptide …
Molecular Modeling of the Class I Human Histocompatibility Molecule HLA‐A2 Presenting an Allele‐Specific Nonapeptide from Influenza Matrix Protein
N Zimmermann, O Rötzschke, K Falk… - … Edition in English, 1992 - Wiley Online Library
The conformation is not α‐helical, but extended when the antigenic peptide binds in the
pocket of the human major histocompatibility complex (MHC) protein HLA‐A2 of class I. This …
pocket of the human major histocompatibility complex (MHC) protein HLA‐A2 of class I. This …
[HTML][HTML] Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding
GJ Carven, S Chitta, I Hilgert, MM Rushe… - Journal of Biological …, 2004 - ASBMB
Class II major histocompatibility complex (MHC) proteins bind peptides and present them at
the cell surface for interaction with CD4+ T cells as part of the system by which the immune …
the cell surface for interaction with CD4+ T cells as part of the system by which the immune …
Free energy mapping of class I MHC molecules and structural determination of bound peptides
U Sezerman, S Vajda, C Delisi - Protein science, 1996 - Wiley Online Library
Free energy maps of the binding site are constructed for class I major histocompatibility
complex (MHC) proteins, by rotating and translating amino acid probes along the cleft, and …
complex (MHC) proteins, by rotating and translating amino acid probes along the cleft, and …
Ligand-free MHC class I conformation.
T Hansen - Nature Structural Biology, 1998 - europepmc.org
Ligand-free MHC class I conformation. - Abstract - Europe PMC Sign in | Create an account
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[HTML][HTML] Strategic mutations in the class I major histocompatibility complex HLA-A2 independently affect both peptide binding and T cell receptor recognition
TK Baxter, SJ Gagnon, RL Davis-Harrison… - Journal of Biological …, 2004 - ASBMB
Mutational studies of T cell receptor (TCR) contact residues on the surface of the human
class I major histocompatibility complex (MHC) molecule HLA-A2 have identified a" …
class I major histocompatibility complex (MHC) molecule HLA-A2 have identified a" …
Molecular modeling and simulations of major histocompatibility complex class I protein–peptide interactions
The Major Histocompatibility Complex (MHC) is a gene cluster, which is to date the most
polymorphic section of the genome to have been encountered. The class I and class II …
polymorphic section of the genome to have been encountered. The class I and class II …
Analysis of the structure of naturally processed peptides bound by class I and class II major histocompatibility complex molecules.
E Appella, EA Padlan, DF Hunt - Exs, 1995 - europepmc.org
Antigen-specific T-cell responses require antigenic peptides presented on the cell surface
by the major histocompatibility complex (MHC) molecules. The structural characteristics of …
by the major histocompatibility complex (MHC) molecules. The structural characteristics of …