Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants

DY Chao, Y Chen, J Chen, S Shi, Z Chen, C Wang… - PLoS …, 2014 - journals.plos.org
Inorganic arsenic is a carcinogen, and its ingestion through foods such as rice presents a
significant risk to human health. Plants chemically reduce arsenate to arsenite. Using …

Hyperaccumulation of arsenic in the shoots of Arabidopsis silenced for arsenate reductase (ACR2)

OP Dhankher, BP Rosen… - Proceedings of the …, 2006 - National Acad Sciences
Endogenous plant arsenate reductase (ACR) activity converts arsenate to arsenite in roots,
immobilizing arsenic below ground. By blocking this activity, we hoped to construct plants …

Natural variation in arsenate tolerance identifies an arsenate reductase in Arabidopsis thaliana

E Sánchez-Bermejo, G Castrillo, B Del Llano… - Nature …, 2014 - nature.com
The enormous amount of environmental arsenic was a major factor in determining the
biochemistry of incipient life forms early in the Earth's history. The most abundant chemical …

New molecular mechanisms to reduce arsenic in crops

ER Lindsay, FJM Maathuis - Trends in Plant Science, 2017 - cell.com
Arsenic is toxic to all life forms and is a potent carcinogen. Its accumulation in crop plants
and subsequent consumption poses a serious threat to public health worldwide. Recent …

Heterologous expression of the yeast arsenite efflux system ACR3 improves Arabidopsis thaliana tolerance to arsenic stress

W Ali, JC Isner, SV Isayenkov, W Liu, FJ Zhao… - New …, 2012 - Wiley Online Library
Arsenic contamination has a negative impact on crop cultivation and on human health. As
yet, no proteins have been identified in plants that mediate the extrusion of arsenic. Here, we …

OsHAC1; 1 and OsHAC1; 2 function as arsenate reductases and regulate arsenic accumulation

S Shi, T Wang, Z Chen, Z Tang, Z Wu, DE Salt… - Plant …, 2016 - academic.oup.com
Rice is a major dietary source of the toxic metalloid arsenic (As). Reducing its accumulation
in rice (Oryza sativa) grain is of critical importance to food safety. Rice roots take up arsenate …

OsHAC4 is critical for arsenate tolerance and regulates arsenic accumulation in rice

J Xu, S Shi, L Wang, Z Tang, T Lv, X Zhu… - New …, 2017 - Wiley Online Library
Soil contamination with arsenic (As) can cause phytotoxicity and elevated As accumulation
in rice grain. Here, we used a forward genetics approach to investigate the mechanism of …

Dissecting the components controlling root‐to‐shoot arsenic translocation in Arabidopsis thaliana

C Wang, GN Na, ES Bermejo, Y Chen… - New …, 2018 - Wiley Online Library
Arsenic (As) is an important environmental and food‐chain toxin. We investigated the key
components controlling As accumulation and tolerance in Arabidopsis thaliana. We tested …

A Vacuolar Arsenite Transporter Necessary for Arsenic Tolerance in the Arsenic Hyperaccumulating Fern Pteris vittata Is Missing in Flowering Plants

E Indriolo, GN Na, D Ellis, DE Salt, JA Banks - The Plant Cell, 2010 - academic.oup.com
The fern Pteris vittata tolerates and hyperaccumulates exceptionally high levels of the toxic
metalloid arsenic, and this trait appears unique to the Pteridaceae. Once taken up by the …

Arsenic transport in rice and biological solutions to reduce arsenic risk from rice

Y Chen, YH Han, Y Cao, YG Zhu… - Frontiers in plant …, 2017 - frontiersin.org
Rice (Oryza sativa L.) feeds∼ 3 billion people. Due to the wide occurrence of arsenic (As)
pollution in paddy soils and its efficient plant uptake, As in rice grains presents health risks …