BACKGROUND: Reducing nebulisation times for tobramycin solution for inhalation in cystic
fibrosis (CF) may improve compliance. METHODS: In this single-dose, open-label, two-way …

Aerosolized tobramycin has been extensively used in cystic fibrosis (CF) patients in order to
directly deliver the antibiotic to the endobronchial site of infection, and decrease toxicity by …

The inhalation of tobramycin is part of current cystic fibrosis (CF) therapy. Local therapy with
inhaled antibiotics has demonstrated improvements in pulmonary function. Current …

Summary Introduction TOBI® Podhaler™ is a capsule‐based drug‐device combination
(tobramycin inhalation powder [TIP] 28 mg capsules via unit‐dose dry powder T‐326 Inhaler …

Background: Tobramycin inhalation powder (TIP) was reported to be effective in two Phase
III studies in patients with cystic fibrosis (CF) chronically infected with Pseudomonas …

Study objective Tobramycin is commonly used to treat respiratory tract infections in patients
with cystic fibrosis. We designed a study to determine the pharmacokinetics and safety of …

Tobramycin inhalation solution is used to treat chronic Pseudomonas aeruginosa lung
infection in cystic fibrosis (CF) patients. We evaluated the efficacy and safety of a novel, light …

Background There are no published data on real-life clinical experience comparing inhaled
antibiotic therapy via new rapid delivery systems with nebulised antibiotic therapy in CF …

Background and aim Progressive respiratory failure due to Pseudomonas aeruginosa
colonization is the most significant morbidity in patients with cystic fibrosis (CF). This trial …

Forteen commercially available jet and ultrasonic nebulizers were investigated with the aim
to select the most suitable type of apparatus for the inhalation of a 10% tobramycin solution …