[HTML][HTML] Role of bile acids in liver diseases mediated by the gut microbiome

JW Shao, TT Ge, SZ Chen, G Wang… - World journal of …, 2021 - ncbi.nlm.nih.gov
The intensive crosstalk between the liver and the intestine performs many essential
functions. This crosstalk is important for natural immune surveillance, adaptive immune …

Role of bile acids in overweight and obese children and adolescents

C Giannini, C Mastromauro, S Scapaticci… - Frontiers in …, 2022 - frontiersin.org
Bile acids (BAs) are amphipathic molecules synthetized in the liver. They are primarily
involved in the digestion of nutrients. Apart from their role in dietary lipid absorption, BAs …

Emerging roles of bile acids in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma

Z Xun, X Yao, Q Ou - Cellular & Molecular Immunology, 2023 - nature.com
Bile acids (BAs) are cholesterol-derived molecules that are produced in the liver, secreted
into the duodenum, absorbed by the small intestine and recycled back to the liver [1]. BAs …

Bile acids as signaling molecules

T Claudel, M Trauner - The Liver: Biology and Pathobiology, 2020 - Wiley Online Library
Insights into the signaling functions of bile acids via a broad range of membrane and nuclear
receptors have profoundly changed our understanding of liver physiology and the …

The physiological importance of bile acid structure and composition on glucose homeostasis

S Higuchi - Current Diabetes Reports, 2020 - Springer
Abstract Purpose of Review Studies have identified several effects of bile acids (BAs) in
glucose homeostasis, energy expenditure, and body weight control, through receptor …

[HTML][HTML] Bile acid metabolism regulatory network orchestrates bone homeostasis

T Xiang, Z Deng, C Yang, J Tan, C Dou, F Luo… - Pharmacological …, 2023 - Elsevier
Bile acids (BAs), synthesized in the liver and modified by the gut microbiota, have been
widely appreciated not only as simple lipid emulsifiers, but also as complex metabolic …

Emerging roles of bile acids in control of intestinal functions

J Yang, A Palmiotti, F Kuipers - Current Opinion in Clinical …, 2021 - journals.lww.com
Specific bile acids act as important signalling molecules affecting whole body metabolism,
specific transport processes and immunity in different segments of the intestinal tract. Their …

Bile acids: a bridge linking gut microbiota and NAFLD

J Zhang, C Wang, X Ji, F Wu, Z Lin… - Advanced Gut & …, 2022 - Wiley Online Library
Nowadays, nonalcoholic fatty liver disease (NAFLD) becomes the most common cause of
liver disease worldwide. Mounting evidence indicates that dysbiosis contributes to the …

therapeutic aspects of bile acid signalling in the gut‐liver axis

B Simbrunner, M Trauner… - Alimentary Pharmacology …, 2021 - Wiley Online Library
Background Bile acids are important endocrine modulators of intestinal and hepatic
signalling cascades orchestrating critical pathophysiological processes in various liver …

Cross-talk between bile acids and intestinal microbiota in host metabolism and health

Y Nie, J Hu, X Yan - Journal of Zhejiang University-SCIENCE B, 2015 - Springer
Bile acid (BA) is de novo synthesized exclusively in the liver and has direct or indirect
antimicrobial effects. On the other hand, the composition and size of the BA pool can be …