Age and sex are risk factors of Alzheimer's disease (AD). Among the neurotransmitter
systems, gamma-aminobutyric acid (GABA) has been implicated in AD pathogenesis but the …

In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …

Functioning at the interface between the nervous and immune systems, in the amyloid-
depositing brain, astrocytes become hypertrophic and accumulate around senile plaques …

Gamma‐hydroxy‐butyric acid (GABA) and glutamate are neurotransmitters with essential
importance for cognitive processing. Here, we investigate relationships between GABA …

Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by beta-amyloid
plaques (Aβ), neurofibrillary tangles (NFT), and neuroinflammation. Data have demonstrated …

Recent research had shown a correlation between aging and decreasing Gamma‐
aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain. However, how …

Conflicting evidence suggest that perturbations of GABAergic neurotransmission play crucial
roles in disrupting cortical neuronal network oscillations, memory, and cognitive deficits in …

Background Neuronal hyperactivity related to β-amyloid (Aβ) is considered an early warning
sign of Alzheimer disease (AD). Although increasing evidence supports this opinion, the …

A promising direction in the research on Alzheimer's Disease (AD) is the identification of
biomarkers that better inform the disease progression of AD. However, the performance of …

Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …