Neuronal network dysfunction is increasingly recognized as an early symptom in
Alzheimer's disease (AD) and may provide new entry points for diagnosis and intervention …

Recent findings show that parvalbumin (PV) interneuron function is impaired in Alzheimer's
disease (AD), and that this impairment in PV function can be linked to network dysfunction …

Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique
morphological and functional properties that allow them to precisely control local circuitry …

Several lines of evidence imply changes in inhibitory interneuron connectivity and
subsequent alterations in oscillatory network activities in the pathogenesis of Alzheimer's …

Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive
decline. These impairments correlate with early alterations in neuronal network activity in AD …

Hippocampal atrophy and neuron loss are commonly found in Alzheimer's disease (AD).
However, the underlying molecular mechanisms and the fate in the AD hippocampus of …

Alzheimer's disease (AD) is the most common neurodegenerative disease and has an
insidious onset. Exploring the characteristics and mechanism of the early symptoms of AD …

Interneurons, key regulators of hippocampal neuronal network excitability and
synchronization, are lost in advanced stages of Alzheimer's disease (AD). Given that …

Specific neuronal networks are preferentially affected in the early stages of Alzheimer's
disease (AD). The distinct subpopulations of hippocampal inhibitory GABAergic system have …

Alzheimer's disease (AD) results in cognitive decline and altered network activity, but the
mechanisms are unknown. We studied human amyloid precursor protein (hAPP) transgenic …