The intricate role of CXCR4 in cancer
S Chatterjee, BB Azad, S Nimmagadda - Advances in cancer research, 2014 - Elsevier
Chemokines mediate numerous physiological and pathological processes related primarily
to cell homing and migration. The chemokine CXCL12, also known as stromal cell-derived …
to cell homing and migration. The chemokine CXCL12, also known as stromal cell-derived …
[HTML][HTML] Duality of B cell-CXCL13 axis in tumor immunology
AJ Rubio, T Porter, X Zhong - Frontiers in Immunology, 2020 - frontiersin.org
Tumor immunity is a rapidly evolving area of research consisting of many possible
permutations of immune cell tumor interactions that are dependent upon cell type, tumor …
permutations of immune cell tumor interactions that are dependent upon cell type, tumor …
Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis
The chemokine stroma-derived factor (SDF-1/CXCL12) plays multiple roles in tumor
pathogenesis. It has been demonstrated that CXCL12 promotes tumor growth and …
pathogenesis. It has been demonstrated that CXCL12 promotes tumor growth and …
Chemokines and their receptors as therapeutic targets: the role of the SDF-1/CXCR4 axis
J Juarez, L Bendall, K Bradstock - Current pharmaceutical …, 2004 - ingentaconnect.com
SDF-1 and CXCR4 are an important chemokine ligand/receptor pair, which play a crucial
role in numerous biological processes including hematopoiesis, cardiogenesis …
role in numerous biological processes including hematopoiesis, cardiogenesis …
[HTML][HTML] CXCL5: A coachman to drive cancer progression
J Deng, R Jiang, E Meng, H Wu - Frontiers in Oncology, 2022 - frontiersin.org
Chemokines are a class of pro-inflammatory cytokines that can recruit and activate
chemotactic cells. C‐X‐C motif chemokine ligand 5 (CXCL5) is a member of the chemokine …
chemotactic cells. C‐X‐C motif chemokine ligand 5 (CXCL5) is a member of the chemokine …
Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12
Although chemokines are well established to function in immunity and endothelial cell
activation and proliferation, a rapidly growing literature suggests that CXC Chemokine …
activation and proliferation, a rapidly growing literature suggests that CXC Chemokine …
[HTML][HTML] CXCL11 correlates with immune infiltration and impacts patient immunotherapy efficacy: A pan-cancer analysis
Y Li, S Han, B Wu, C Zhong, Y Shi, C Lv, L Fu… - Frontiers in …, 2022 - frontiersin.org
Background Immunotherapy has achieved great success in cancer. Nevertheless, many
patients cannot benefit from immune checkpoint blockade therapy because of the scantiness …
patients cannot benefit from immune checkpoint blockade therapy because of the scantiness …
[HTML][HTML] CXCR3 in carcinoma progression
CXCR3 is a G-protein coupled receptor which binds to ELR-negative CXC chemokines that
have been found to impact immune responses, vascular develop, and wound repair. More …
have been found to impact immune responses, vascular develop, and wound repair. More …
The CXCR3 targeting chemokine CXCL11 has potent antitumor activity in vivo involving attraction of CD8+ T lymphocytes but not inhibition of angiogenesis
PJ Hensbergen, PGJTB Wijnands… - Journal of …, 2005 - journals.lww.com
The IFN-γ-inducible and CXCR3-targeting human CXC chemokines CXCL9 (Mig) and
CXCL10 (IP10) have potent antitumor activity through attraction of cytotoxic T lymphocytes …
CXCL10 (IP10) have potent antitumor activity through attraction of cytotoxic T lymphocytes …