Cancer is a multi-step disease caused by the accumulation of genetic mutations and/or
epigenetic changes, and is the biggest challenge around the world. Cytokines, including …

CXCR6 is a receptor for the chemokine CXCL16, which exists as a membrane or soluble
form. CXCR6 is a marker for resident memory T (TRM) cells that plays a role in …

The development of cancer is a multistep and complex process involving interactions
between tumor cells and the tumor microenvironment (TME). CXC chemokine ligand 13 …

Background Colorectal cancer (CRC), which frequently metastasizes to the liver, is one of
the three leading causes of cancer-related deaths worldwide. Growing evidence suggests …

Chemokines exert their multifunctional role in several physiologic and pathologic processes
through interaction with their specific receptors. Much evidence have revealed that …

The chemokine CXCL14 is a highly conserved, homeostatic chemokine that is constitutively
expressed in skin epithelia. Responsible for immune cell recruitment and maturation, as well …

Chemokines, small pro-inflammatory chemoattractant cytokines that bind to specific G-
protein-coupled seven-span transmembrane receptors, are major regulators of cell …

Tumors are dynamic tissue masses, so requiring continuous exposure to the host cells,
nurturing them into pave a path for tumor growth and metastasis. CXC chemokine ligand 12 …

The chemokine CXCL8 has been found to play an important role in tumor progression in
recent years. CXCL8 activates multiple intracellular signaling pathways by binding to its …

It is known that the chemokine receptor CXCR7 (RDC1) can be engaged by both
chemokines CXCL12 (SDF-1) and CXCL11 (I-TAC), but the exact expression pattern and …