Hyaluronic acid (HA) with one reactive moiety grafted to the backbone is a commonly used
matrix in tissue engineering. The addition of a second orthogonal moiety to the backbone …

Object Therapies that use bioactive materials as replacement extracellular matrices may
hold the potential to mitigate the inhibition of regeneration observed after central nervous …

Millions of Americans suffer from nervous system injuries. Hydrogels have been investigated
to (1) bridge nerve gaps;(2) act as scaffolds for bioactive molecule delivery or cell …

Either oriented architecture or viscoelasticity is pivotal to neurogenesis, thus, native neural
extracellular matrix derived-hyaluronan hydrogels with nano-orientation and viscoelasticity …

Our aim was to investigate axonal outgrowth from different tissue models on soft
biomaterials based on hyaluronic acid (HA). We hypothesized that HA-based hydrogels …

Numerous biomaterials based on extracellular matrix-components have been developed. It
was our aim to investigate whether a hyaluronic acid–based hydrogel improves neuronal …

In this work, a novel enzymatically crosslinked injectable hydrogel comprising hyaluronic
acid (HyA), dopamine (DA), and 3-(4-hydroxyphenyl) propionic acid (HPA) conjugates was …

Hyaluronic acid (HA) is a polysaccharide in the extracellular matrix (ECM) that controls cell
function in neural tissue through cellular receptors. These functions include migration …

Hydrogels are an important class of biomaterials that have the potential to be used as three-
dimensional tissue engineering scaffolds for regenerative medicine. This is especially true in …

While in the past hyaluronic acid (HA) was considered a passive component with a primarily
structural role in tissues, research over the past few decades has revealed its diverse and …